Development Level

Tbio 132 | 11,445
Tchem 27 | 1,598
Tclin 21 | 613
Tdark 8 | 6,588

Collection

GPCR: IDG Consortium (Complete... 2 | 25
Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, incomple... 8 | 499
abnormal behavior 5 | 298
decreased total body fat amoun... 5 | 207
enlarged heart 5 | 210
increased bone mineral content 5 | 108
abnormal heart morphology 4 | 162
preweaning lethality, complete... 4 | 979
abnormal eye morphology 3 | 68
abnormal seminal vesicle morph... 3 | 114
decreased startle reflex 3 | 75
decreased vertical activity 3 | 208
abnormal bone structure 2 | 187
abnormal coat appearance 2 | 31
decreased body length 2 | 101
decreased grip strength 2 | 116
embryonic lethality prior to t... 2 | 278
enlarged spleen 2 | 41
hyperactivity 2 | 148
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased heart weight 2 | 62
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
male infertility 2 | 123
tremors 2 | 39
abnormal cornea morphology 1 | 31
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal pancreas morphology 1 | 13
abnormal placenta size 1 | 20
abnormal response to new envir... 1 | 10
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal tail movements 1 | 12
abnormal urinary bladder morph... 1 | 11
abnormal urination 1 | 1
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent startle reflex 1 | 24
absent testes 1 | 6
absent vibrissae 1 | 12
decreased T cell number 1 | 15
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased cardiac muscle contr... 1 | 11
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased CD4-positive, alpha ... 1 | 4
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased spleen weight 1 | 10
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 145 | 11,493
osteosarcoma 114 | 7,950
ovarian cancer 109 | 8,520
glioblastoma 102 | 5,792
psoriasis 97 | 6,694
medulloblastoma, large-cell 91 | 6,241
lung cancer 83 | 4,740
Cancer 77 | 2,499
lung carcinoma 73 | 2,843
ependymoma 72 | 4,679
atypical teratoid / rhabdoid tumor 71 | 5,112
Astrocytoma, Pilocytic 63 | 3,081
malignant mesothelioma 61 | 3,232
adult high grade glioma 60 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 60 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 59 | 2,989
invasive ductal carcinoma 59 | 2,951
non-small cell lung cancer 59 | 2,890
interstitial cystitis 56 | 2,312
pancreatic cancer 55 | 2,398
Breast cancer 49 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 47 | 2,955
ulcerative colitis 47 | 1,819
group 3 medulloblastoma 46 | 4,104
lung adenocarcinoma 43 | 2,716
tuberculosis 43 | 2,010
cutaneous lupus erythematosus 40 | 1,057
subependymal giant cell astrocytoma 39 | 2,287
primitive neuroectodermal tumor 38 | 3,035
diabetes mellitus 36 | 1,728
oligodendroglioma 36 | 2,850
dermatomyositis 35 | 966
ductal carcinoma in situ 34 | 1,745
Kidney cancer 33 | 2,613
primary pancreatic ductal adenocarcinoma 33 | 1,109
juvenile dermatomyositis 31 | 1,187
astrocytic glioma 29 | 2,597
group 4 medulloblastoma 29 | 1,855
Rheumatoid arthritis 28 | 1,191
cystic fibrosis 27 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,962
breast carcinoma 26 | 1,638
pituitary cancer 26 | 1,972
Multiple Sclerosis 25 | 540
Multiple myeloma 25 | 1,332
esophageal adenocarcinoma 25 | 737
primary Sjogren syndrome 24 | 735
Hypersensitivity reaction type II disease 23 | 253
Schizophrenia 23 | 1,160
pediatric high grade glioma 23 | 1,064
Autosomal recessive predisposition 22 | 1,442
Pick disease 22 | 1,894
acute quadriplegic myopathy 22 | 1,158
astrocytoma 22 | 1,146
gastric carcinoma 22 | 807
Duchenne muscular dystrophy 21 | 601
colon cancer 21 | 1,478
Liver Cirrhosis, Experimental 20 | 769
active Crohn's disease 20 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 20 | 510
Arthritis 18 | 290
Alzheimer's disease 17 | 658
adrenocortical carcinoma 17 | 1,428
Waldenstrons macroglobulinemia 16 | 765
Atopic dermatitis 15 | 952
Down syndrome 15 | 499
nasopharyngeal carcinoma 15 | 1,058
Anemia 14 | 365
Human immunodeficiency virus infectious disease 14 | 138
active ulcerative colitis 14 | 764
acute myeloid leukemia 14 | 783
Ankylosing spondylitis 12 | 140
Breast Neoplasms 12 | 445
Mammary Neoplasms 12 | 425
Vascular disease 12 | 319
progressive supranuclear palsy 12 | 676
spina bifida 12 | 1,074
Endometriosis 11 | 540
Lymphoproliferative syndrome 11 | 58
mucosa-associated lymphoid tissue lymphoma 11 | 484
posterior fossa group A ependymoma 11 | 468
Acquired immunodeficiency syndrome 10 | 197
Behcet's disease 10 | 89
Chronic Lymphocytic Leukemia 10 | 262
Intellectual disability 10 | 1,016
Juvenile rheumatoid arthritis 10 | 111
Kidney disease 10 | 430
Obesity 10 | 678
aldosterone-producing adenoma 10 | 665
pancreatic carcinoma 10 | 562
periodontitis 10 | 293
Dull intelligence 9 | 645
Epilepsy 9 | 792
Low intelligence 9 | 645
Melanoma 9 | 711
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
Skin cancer 9 | 469
non primary Sjogren syndrome sicca 9 | 891

Tissue

Blood and immune system 178 | 16,909
Endocrine System 178 | 18,159
Female tissues 178 | 17,400
Urinary Tract 178 | 16,678
Digestive Tract 177 | 17,369
Liver and Pancreas 177 | 16,750
Male tissues 177 | 17,142
Respiratory system 177 | 16,393
Skin and soft tissues 177 | 17,230
Cardiovascular System 175 | 15,192
Nervous System 175 | 16,725

Target Family

Non-IDG 136 | 12,091
Enzyme 17 | 4,145
Transporter 15 | 473
Ion Channel 7 | 344
Kinase 7 | 634
GPCR 6 | 408

CSPA Cell Line

Jurkat 188 | 188
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tchem Ion Channel -2.28525 197.9 203
Leukocyte-associated immunoglobulin-like receptor 1 LAIR1 Tbio Non-IDG -1.74760 64.2 487
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Solute carrier family 12 member 7 SLC12A7 Tbio Transporter -1.46102 28.2 156
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Prostaglandin D2 receptor 2 PTGDR2 Tchem GPCR -2.38441 265.9 439
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
Zinc transporter ZIP10 SLC39A10 Tbio Transporter -1.20558 16.3 102