Development Level

Tbio 93 | 11,445
Tchem 26 | 1,598
Tclin 20 | 613
Tdark 7 | 6,588

Collection

GPCR: IDG Consortium (Targets) 2 | 126
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal behavior 5 | 298
decreased total body fat amoun... 5 | 207
preweaning lethality, incomple... 4 | 499
decreased vertical activity 3 | 208
enlarged heart 3 | 210
enlarged spleen 3 | 41
increased bone mineral content 3 | 108
increased mean corpuscular vol... 3 | 92
preweaning lethality, complete... 3 | 979
abnormal bone structure 2 | 187
cardiovascular system phenotyp... 2 | 36
decreased startle reflex 2 | 75
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased circulating choleste... 2 | 66
increased lean body mass 2 | 172
abnormal cecum morphology 1 | 7
abnormal coat appearance 1 | 31
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal urination 1 | 1
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
absent vibrissae 1 | 12
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased cardiac muscle contr... 1 | 11
decreased circulating bilirubi... 1 | 19
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
hypoactivity 1 | 132
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
pallor 1 | 34
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 114 | 11,493
osteosarcoma 90 | 7,950
ovarian cancer 90 | 8,520
glioblastoma 82 | 5,792
lung carcinoma 75 | 2,843
Cancer 72 | 2,499
lung cancer 65 | 4,740
psoriasis 63 | 6,694
medulloblastoma, large-cell 60 | 6,241
interstitial cystitis 54 | 2,312
Astrocytoma, Pilocytic 53 | 3,081
tuberculosis 53 | 2,010
atypical teratoid / rhabdoid tumor 52 | 5,112
invasive ductal carcinoma 51 | 2,951
malignant mesothelioma 47 | 3,232
non-small cell lung cancer 47 | 2,890
ependymoma 45 | 4,679
Breast cancer 43 | 3,578
pancreatic cancer 42 | 2,398
subependymal giant cell astrocytoma 42 | 2,287
ulcerative colitis 42 | 1,819
adult high grade glioma 40 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 40 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,989
lung adenocarcinoma 37 | 2,716
diabetes mellitus 30 | 1,728
juvenile dermatomyositis 30 | 1,187
Rheumatoid arthritis 28 | 1,191
dermatomyositis 28 | 966
group 3 medulloblastoma 28 | 4,104
cutaneous lupus erythematosus 27 | 1,057
cystic fibrosis 27 | 1,696
Kidney cancer 26 | 2,613
oligodendroglioma 26 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
primary pancreatic ductal adenocarcinoma 26 | 1,109
Liver Cirrhosis, Experimental 25 | 769
Multiple myeloma 25 | 1,332
primitive neuroectodermal tumor 25 | 3,035
gastric carcinoma 24 | 807
group 4 medulloblastoma 24 | 1,855
mucosa-associated lymphoid tissue lymphoma 24 | 484
Multiple Sclerosis 23 | 540
ductal carcinoma in situ 22 | 1,745
esophageal adenocarcinoma 22 | 737
pediatric high grade glioma 22 | 1,064
primary Sjogren syndrome 21 | 735
Duchenne muscular dystrophy 20 | 601
Hypersensitivity reaction type II disease 20 | 253
astrocytic glioma 20 | 2,597
Schizophrenia 19 | 1,160
Kidney disease 18 | 430
astrocytoma 18 | 1,146
Alzheimer's disease 17 | 658
Pick disease 17 | 1,894
acute quadriplegic myopathy 17 | 1,158
Autosomal recessive predisposition 16 | 1,442
Anemia 15 | 365
Arthritis 15 | 290
Asthma 15 | 385
Human immunodeficiency virus infectious disease 15 | 138
Waldenstrons macroglobulinemia 14 | 765
active ulcerative colitis 14 | 764
adrenocortical carcinoma 14 | 1,428
breast carcinoma 14 | 1,638
nasopharyngeal carcinoma 14 | 1,058
Atherosclerosis 13 | 291
Down syndrome 13 | 499
Vascular disease 13 | 319
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 510
colon cancer 13 | 1,478
head and neck cancer and chronic obstructive pulmonary disease 13 | 239
Breast Neoplasms 12 | 445
Endometriosis 12 | 540
Mammary Neoplasms 12 | 425
active Crohn's disease 12 | 922
acute myeloid leukemia 12 | 783
pancreatic carcinoma 12 | 562
Hypertension 11 | 396
Inflammatory bowel disease 11 | 151
Liver disease 11 | 237
periodontitis 11 | 293
pituitary cancer 11 | 1,972
Dermatitis 10 | 157
Malaria 10 | 160
Thrombocytopenia 10 | 197
spina bifida 10 | 1,074
Cerebrovascular disease 9 | 238
Coronary artery disease 9 | 268
Liver Cirrhosis 9 | 181
Neurodegenerative disease 9 | 414
Obesity 9 | 678
non primary Sjogren syndrome sicca 9 | 891
Barrett's esophagus 8 | 182
Liver cancer 8 | 604
Vasculitis 8 | 80
hepatocellular carcinoma 8 | 547
posterior fossa group A ependymoma 8 | 468
progressive supranuclear palsy 8 | 676

Tissue

Blood and immune system 142 | 16,909
Digestive Tract 142 | 17,369
Skin and soft tissues 142 | 17,230
Endocrine System 141 | 18,159
Respiratory system 141 | 16,393
Urinary Tract 141 | 16,678
Female tissues 140 | 17,400
Liver and Pancreas 140 | 16,750
Male tissues 140 | 17,142
Nervous System 139 | 16,725
Cardiovascular System 137 | 15,192

Target Family

Non-IDG 105 | 12,091
Transporter 15 | 473
Enzyme 13 | 4,145
GPCR 7 | 408
Ion Channel 3 | 344
Kinase 2 | 634
Transcription Factor 1 | 1,400

CSPA Cell Line

HL-60 146 | 146
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Leukocyte-associated immunoglobulin-like receptor 1 LAIR1 Tbio Non-IDG -1.74760 64.2 487
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
CD276 antigen CD276 Tbio Non-IDG -3.03140 785.5 481
Post-GPI attachment to proteins factor 6 TMEM8A Tdark Non-IDG -0.56820 3.55 16
Zinc transporter ZIP6 SLC39A6 Tbio Transporter -1.66663 50.0 172