Development Level

Tbio 205 | 10,625
Tchem 58 | 1,890
Tdark 34 | 7,003
Tclin 32 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 3 | 24
GPCR: IDG Consortium (Targets) 2 | 128
Ion Channel: IDG Consortium (Targets) 2 | 102

IMPC Phenotype

preweaning lethality, complete... 14 | 633
preweaning lethality, incomple... 12 | 260
abnormal behavior 9 | 226
impaired glucose tolerance 6 | 52
decreased bone mineral density 5 | 126
decreased lean body mass 5 | 195
embryonic lethality prior to t... 5 | 187
enlarged heart 5 | 111
increased or absent threshold ... 5 | 128
decreased total body fat amoun... 4 | 186
abnormal embryo size 3 | 112
decreased body weight 3 | 174
decreased circulating glucose ... 3 | 121
decreased eosinophil cell numb... 3 | 41
decreased erythrocyte cell num... 3 | 43
decreased leukocyte cell numbe... 3 | 54
decreased monocyte cell number 3 | 28
decreased rib number 3 | 59
enlarged spleen 3 | 26
hypoactivity 3 | 89
improved glucose tolerance 3 | 56
increased fasted circulating g... 3 | 68
increased mean corpuscular hem... 3 | 93
increased mean corpuscular vol... 3 | 91
tremors 3 | 34
abnormal QRS complex 2 | 25
abnormal bone structure 2 | 131
abnormal coat appearance 2 | 25
abnormal eye morphology 2 | 38
abnormal gait 2 | 51
abnormal limb position 2 | 3
abnormal pericardium morpholog... 2 | 11
abnormal retina morphology 2 | 100
abnormal sleep behavior 2 | 63
cardiovascular system phenotyp... 2 | 35
corneal opacity 2 | 25
decreased bone mineral content 2 | 157
decreased grip strength 2 | 123
embryonic lethality prior to o... 2 | 148
female infertility 2 | 34
increased B cell number 2 | 23
increased body weight 2 | 42
increased bone mineral content 2 | 92
increased circulating alkaline... 2 | 119
increased circulating choleste... 2 | 53
increased circulating iron lev... 2 | 25
increased circulating potassiu... 2 | 31
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 24
increased erythrocyte cell num... 2 | 26
increased exploration in new e... 2 | 56
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased lean body mass 2 | 107
straub tail 2 | 26
thrombocytopenia 2 | 46
vertebral fusion 2 | 23
abnormal embryo turning 1 | 15
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal response to new envir... 1 | 8
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal startle reflex 1 | 14
abnormal tail movements 1 | 12
abnormal thoracic vertebrae mo... 1 | 16
craniofacial phenotype 1 | 9
decreased CD4-positive, alpha ... 1 | 19
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased cardiac muscle contr... 1 | 5
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating triglyce... 1 | 83
decreased heart rate 1 | 10
decreased mean corpuscular hem... 1 | 34
enlarged heart atrium 1 | 2
enlarged lymph nodes 1 | 27
hydrometra 1 | 13
hydrops fetalis 1 | 22
impaired righting response 1 | 19
increased NK cell number 1 | 19
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased circulating glycerol... 1 | 11
increased mean platelet volume 1 | 19
increased sacral vertebrae num... 1 | 62
lethargy 1 | 5
long tibia 1 | 13
microphthalmia 1 | 15
polycystic kidney 1 | 9
premature death 1 | 5
prenatal lethality prior to he... 1 | 64
trunk curl 1 | 15

Disease

ovarian cancer 217 | 8,491
osteosarcoma 184 | 7,933
glioblastoma 179 | 5,572
medulloblastoma, large-cell 160 | 6,234
psoriasis 143 | 6,685
lung cancer 133 | 4,473
atypical teratoid / rhabdoid tumor 128 | 4,369
malignant mesothelioma 115 | 3,163
lung carcinoma 114 | 2,844
pilocytic astrocytoma 110 | 3,086
Breast cancer 109 | 3,098
invasive ductal carcinoma 107 | 2,950
Cancer 106 | 2,346
pediatric high grade glioma 99 | 2,712
Carcinoma 97 | 2,147
intraductal papillary-mucinous neoplasm (IPMN) 97 | 3,289
lung adenocarcinoma 94 | 2,714
non-small cell lung cancer 94 | 2,798
pancreatic cancer 91 | 2,300
intraductal papillary-mucinous adenoma (IPMA) 89 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 89 | 2,988
oligodendroglioma 88 | 2,849
ulcerative colitis 88 | 2,087
ependymoma 77 | 2,514
interstitial cystitis 77 | 2,299
primitive neuroectodermal tumor 74 | 3,031
subependymal giant cell astrocytoma 73 | 2,287
pituitary cancer 66 | 1,972
cystic fibrosis 64 | 1,670
group 4 medulloblastoma 64 | 1,875
primary pancreatic ductal adenocarcinoma 64 | 1,271
breast carcinoma 63 | 1,614
ductal carcinoma in situ 62 | 1,745
astrocytoma 57 | 1,493
astrocytic glioma 56 | 2,241
diabetes mellitus 53 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 53 | 1,795
group 3 medulloblastoma 52 | 2,254
posterior fossa group A ependymoma 52 | 1,511
colon cancer 51 | 1,475
Pick disease 50 | 1,893
juvenile dermatomyositis 50 | 1,189
adrenocortical carcinoma 49 | 1,427
adult high grade glioma 47 | 2,148
sonic hedgehog group medulloblastoma 45 | 1,482
gastric carcinoma 44 | 832
tuberculosis 41 | 1,563
Multiple myeloma 38 | 1,327
acute quadriplegic myopathy 38 | 1,157
cutaneous lupus erythematosus 38 | 1,056
dermatomyositis 38 | 966
Duchenne muscular dystrophy 35 | 602
active Crohn's disease 34 | 918
esophageal adenocarcinoma 34 | 737
medulloblastoma 34 | 1,524
posterior fossa group B ependymoma 33 | 1,530
atypical teratoid/rhabdoid tumor 32 | 1,095
Alzheimer's disease 31 | 644
Multiple Sclerosis 30 | 498
Rheumatoid Arthritis 30 | 1,170
Mammary Neoplasms 29 | 410
Atopic dermatitis 28 | 944
Down syndrome 28 | 548
autosomal dominant Emery-Dreifuss muscular dystrophy 28 | 499
nasopharyngeal carcinoma 28 | 1,056
acute myeloid leukemia 26 | 785
fibroadenoma 25 | 557
spina bifida 25 | 1,064
aldosterone-producing adenoma 24 | 664
primary Sjogren syndrome 24 | 788
non-small cell lung carcinoma 20 | 413
mucosa-associated lymphoid tissue lymphoma 19 | 480
Endometriosis 18 | 535
Kidney disease 18 | 397
Prostatic Neoplasms 18 | 471
Stomach Neoplasms 18 | 282
pancreatic carcinoma 17 | 567
progressive supranuclear palsy 17 | 674
Asthma 16 | 349
Hypersensitivity reaction type II disease 16 | 235
Obesity 16 | 616
Barrett's esophagus 15 | 185
Waldenstrons macroglobulinemia 15 | 764
non primary Sjogren syndrome sicca 15 | 840
Neoplasm Invasiveness 14 | 127
Peripheral Neuropathy 14 | 303
Schizophrenia 14 | 503
glioblastoma multiforme 14 | 347
Anemia 13 | 252
Atherosclerosis 13 | 275
Colorectal Neoplasms 13 | 217
Coronary artery disease 13 | 240
Arthritis 12 | 248
Cerebrovascular disease 12 | 231
Intellectual disability 12 | 573
Liver carcinoma 12 | 217
Liver disease 12 | 219
Mammary Neoplasms, Experimental 12 | 149
hepatocellular carcinoma 12 | 550
nephrosclerosis 12 | 329

Tissue

Blood and immune system 328 | 17,994
Cardiovascular System 328 | 17,957
Digestive Tract 328 | 18,472
Endocrine System 328 | 18,511
Female tissues 328 | 18,646
Liver and Pancreas 328 | 18,135
Male tissues 328 | 17,968
Nervous System 328 | 18,560
Respiratory system 328 | 17,483
Urinary Tract 328 | 18,443
Skin and soft tissues 326 | 18,114

Target Family

Non-IDG 221 | 11,969
Enzyme 41 | 4,146
Kinase 21 | 634
Transporter 21 | 473
GPCR 16 | 408
Ion Channel 9 | 341

CSPA Cell Line

HEK 329 | 329
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interferon gamma receptor 1 IFNGR1 Tchem Non-IDG -2.19638 160.9 450
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.25806 19000.3 3336
Folate receptor alpha FOLR1 Tchem Non-IDG -2.27944 181.4 235
Sodium/potassium-transporting ATPase subunit beta-3 ATP1B3 Tclin Transporter -1.08214 10.9 189
Prominin-1 PROM1 Tbio Non-IDG -3.27144 1922.5 226
Metalloproteinase inhibitor 1 TIMP1 Tbio Enzyme -3.55219 3513.4 673
Endothelial protein C receptor PROCR Tbio Non-IDG -2.67797 519.6 324
Tyrosine-protein kinase transmembrane receptor ROR2 ROR2 Tbio Kinase -1.84344 79.9 342
Glutamate receptor ionotropic, delta-1 GRID1 Tbio Ion Channel -1.05986 9.38 156
Receptor-type tyrosine-protein phosphatase mu PTPRM Tbio Enzyme -1.82872 68.8 135