Development Level

Tbio 129 | 11,445
Tchem 29 | 1,598
Tclin 21 | 613
Tdark 14 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

abnormal behavior 6 | 298
preweaning lethality, incomple... 6 | 499
preweaning lethality, complete... 5 | 979
abnormal bone structure 4 | 187
decreased total body fat amoun... 4 | 207
enlarged heart 4 | 210
improved glucose tolerance 4 | 79
increased bone mineral content 4 | 108
decreased blood urea nitrogen ... 3 | 51
decreased startle reflex 3 | 75
decreased vertical activity 3 | 208
increased circulating choleste... 3 | 66
increased mean corpuscular vol... 3 | 92
increased or absent threshold ... 3 | 101
abnormal coat appearance 2 | 31
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
abnormal spleen morphology 2 | 55
abnormal vertebrae morphology 2 | 18
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased heart weight 2 | 27
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged lymph nodes 2 | 37
enlarged spleen 2 | 41
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating iron lev... 2 | 30
increased heart rate 2 | 23
tremors 2 | 39
abnormal bone mineralization 1 | 38
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal liver morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal urination 1 | 1
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating unsatura... 1 | 2
decreased eosinophil cell numb... 1 | 24
decreased heart rate 1 | 18
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
impaired glucose tolerance 1 | 75
increased B cell number 1 | 9
increased aggression 1 | 4
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
vertebral fusion 1 | 23

Disease

Carcinoma 142 | 11,493
ovarian cancer 108 | 8,520
glioblastoma 99 | 5,792
osteosarcoma 97 | 7,950
Cancer 91 | 2,499
psoriasis 82 | 6,694
lung cancer 80 | 4,740
lung carcinoma 76 | 2,843
medulloblastoma, large-cell 75 | 6,241
malignant mesothelioma 65 | 3,232
atypical teratoid / rhabdoid tumor 62 | 5,112
ependymoma 62 | 4,679
interstitial cystitis 60 | 2,312
Astrocytoma, Pilocytic 57 | 3,081
invasive ductal carcinoma 56 | 2,951
adult high grade glioma 52 | 3,801
Breast cancer 50 | 3,578
diabetes mellitus 50 | 1,728
non-small cell lung cancer 50 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 48 | 2,955
subependymal giant cell astrocytoma 48 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 47 | 2,989
pancreatic cancer 47 | 2,398
ulcerative colitis 46 | 1,819
group 3 medulloblastoma 45 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 45 | 3,291
lung adenocarcinoma 44 | 2,716
tuberculosis 42 | 2,010
Rheumatoid arthritis 39 | 1,191
juvenile dermatomyositis 37 | 1,187
oligodendroglioma 37 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 36 | 1,962
cutaneous lupus erythematosus 35 | 1,057
astrocytic glioma 34 | 2,597
Multiple Sclerosis 33 | 540
group 4 medulloblastoma 33 | 1,855
Hypersensitivity reaction type II disease 32 | 253
Kidney cancer 32 | 2,613
primitive neuroectodermal tumor 32 | 3,035
dermatomyositis 31 | 966
cystic fibrosis 30 | 1,696
ductal carcinoma in situ 30 | 1,745
primary pancreatic ductal adenocarcinoma 29 | 1,109
breast carcinoma 27 | 1,638
Autosomal recessive predisposition 26 | 1,442
esophageal adenocarcinoma 26 | 737
pituitary cancer 26 | 1,972
Multiple myeloma 25 | 1,332
Schizophrenia 25 | 1,160
gastric carcinoma 25 | 807
primary Sjogren syndrome 25 | 735
Pick disease 24 | 1,894
acute quadriplegic myopathy 23 | 1,158
adrenocortical carcinoma 23 | 1,428
Duchenne muscular dystrophy 22 | 601
active Crohn's disease 21 | 922
astrocytoma 21 | 1,146
pediatric high grade glioma 21 | 1,064
Atopic dermatitis 20 | 952
colon cancer 20 | 1,478
Arthritis 19 | 290
Waldenstrons macroglobulinemia 19 | 765
Down syndrome 18 | 499
Kidney disease 18 | 430
Liver Cirrhosis, Experimental 18 | 769
active ulcerative colitis 17 | 764
Anemia 16 | 365
Asthma 16 | 385
Human immunodeficiency virus infectious disease 15 | 138
Alzheimer's disease 14 | 658
Atherosclerosis 14 | 291
Hepatitis B 14 | 108
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
mucosa-associated lymphoid tissue lymphoma 14 | 484
nasopharyngeal carcinoma 14 | 1,058
Breast Neoplasms 13 | 445
Hypertension 13 | 396
Juvenile rheumatoid arthritis 13 | 111
Liver disease 13 | 237
Mammary Neoplasms 13 | 425
Vascular disease 13 | 319
acute myeloid leukemia 13 | 783
Acquired immunodeficiency syndrome 12 | 197
sarcoidosis 12 | 370
Ankylosing spondylitis 11 | 140
Endometriosis 11 | 540
head and neck cancer and chronic obstructive pulmonary disease 11 | 239
non primary Sjogren syndrome sicca 11 | 891
Barrett's esophagus 10 | 182
Chronic Lymphocytic Leukemia 10 | 262
Coronary artery disease 10 | 268
Dermatitis 10 | 157
Inflammatory bowel disease 10 | 151
Neurodegenerative disease 10 | 414
Obesity 10 | 678
nephrosclerosis 10 | 333
pancreatic carcinoma 10 | 562
Arthritis, Rheumatoid 9 | 174
Bipolar Disorder 9 | 666
periodontitis 9 | 293

Tissue

Endocrine System 179 | 18,159
Skin and soft tissues 179 | 17,230
Blood and immune system 178 | 16,909
Digestive Tract 178 | 17,369
Liver and Pancreas 178 | 16,750
Male tissues 178 | 17,142
Respiratory system 178 | 16,393
Urinary Tract 178 | 16,678
Female tissues 177 | 17,400
Nervous System 175 | 16,725
Cardiovascular System 171 | 15,192

Target Family

Non-IDG 147 | 12,091
Enzyme 18 | 4,145
Transporter 11 | 473
GPCR 7 | 408
Kinase 7 | 634
Ion Channel 2 | 344
Transcription Factor 1 | 1,400

CSPA Cell Line

HDLM-2 193 | 193
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Leukocyte-associated immunoglobulin-like receptor 1 LAIR1 Tbio Non-IDG -1.74760 64.2 487
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.90516 156.1 254
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
UL-16 binding protein 5 RAET1G Tbio Non-IDG -0.77225 5.67 20
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0