Development Level

Tbio 130 | 11,445
Tchem 31 | 1,598
Tdark 18 | 6,588
Tclin 13 | 613

Collection

GPCR: IDG Consortium (Complete... 3 | 25
GPCR: IDG Consortium (Targets) 2 | 126
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, incomple... 8 | 499
preweaning lethality, complete... 7 | 979
abnormal behavior 6 | 298
decreased vertical activity 5 | 208
decreased total body fat amoun... 4 | 207
increased heart weight 4 | 62
abnormal embryo size 3 | 220
abnormal eye morphology 3 | 68
abnormal limb bud morphology 3 | 17
enlarged heart 3 | 210
enlarged spleen 3 | 41
increased bone mineral content 3 | 108
increased circulating triglyce... 3 | 42
increased erythrocyte cell num... 3 | 39
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
abnormal bone structure 2 | 187
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
cardiovascular system phenotyp... 2 | 36
decreased body weight 2 | 161
decreased cardiac muscle contr... 2 | 11
decreased circulating creatini... 2 | 39
decreased eosinophil cell numb... 2 | 24
decreased lean body mass 2 | 135
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased circulating choleste... 2 | 66
increased circulating glycerol... 2 | 9
increased mean corpuscular vol... 2 | 92
pallor 2 | 34
tremors 2 | 39
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal response to new envir... 1 | 10
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
dilated heart left ventricle 1 | 11
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased exploration in new e... 1 | 8
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased total retina thickne... 1 | 4
pale yolk sac 1 | 25
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prolonged PQ interval 1 | 5
syndactyly 1 | 23
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 152 | 11,493
ovarian cancer 132 | 8,520
glioblastoma 112 | 5,792
osteosarcoma 109 | 7,950
medulloblastoma, large-cell 91 | 6,241
Cancer 87 | 2,499
atypical teratoid / rhabdoid tumor 86 | 5,112
ependymoma 85 | 4,679
psoriasis 84 | 6,694
malignant mesothelioma 80 | 3,232
lung cancer 73 | 4,740
lung carcinoma 72 | 2,843
Breast cancer 71 | 3,578
Astrocytoma, Pilocytic 70 | 3,081
invasive ductal carcinoma 68 | 2,951
adult high grade glioma 64 | 3,801
pancreatic cancer 63 | 2,398
non-small cell lung cancer 62 | 2,890
lung adenocarcinoma 61 | 2,716
oligodendroglioma 61 | 2,850
group 3 medulloblastoma 60 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 60 | 2,955
ulcerative colitis 54 | 1,819
cystic fibrosis 53 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 53 | 3,291
interstitial cystitis 51 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 51 | 2,989
astrocytic glioma 50 | 2,597
Kidney cancer 49 | 2,613
subependymal giant cell astrocytoma 47 | 2,287
primary pancreatic ductal adenocarcinoma 45 | 1,109
primitive neuroectodermal tumor 45 | 3,035
ductal carcinoma in situ 43 | 1,745
juvenile dermatomyositis 42 | 1,187
diabetes mellitus 40 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 40 | 1,962
tuberculosis 38 | 2,010
breast carcinoma 33 | 1,638
dermatomyositis 33 | 966
gastric carcinoma 33 | 807
Pick disease 32 | 1,894
pituitary cancer 32 | 1,972
adrenocortical carcinoma 31 | 1,428
colon cancer 30 | 1,478
group 4 medulloblastoma 30 | 1,855
Duchenne muscular dystrophy 29 | 601
acute quadriplegic myopathy 28 | 1,158
nasopharyngeal carcinoma 28 | 1,058
pediatric high grade glioma 28 | 1,064
Alzheimer's disease 24 | 658
Liver Cirrhosis, Experimental 24 | 769
Rheumatoid arthritis 24 | 1,191
Multiple Sclerosis 23 | 540
Multiple myeloma 23 | 1,332
esophageal adenocarcinoma 23 | 737
Atopic dermatitis 22 | 952
active Crohn's disease 21 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 21 | 510
Autosomal recessive predisposition 19 | 1,442
Kidney disease 19 | 430
acute myeloid leukemia 18 | 783
astrocytoma 18 | 1,146
cutaneous lupus erythematosus 18 | 1,057
Hypersensitivity reaction type II disease 17 | 253
active ulcerative colitis 17 | 764
Breast Neoplasms 16 | 445
Down syndrome 16 | 499
Vascular disease 16 | 319
Becker muscular dystrophy 15 | 191
Mammary Neoplasms 15 | 425
Schizophrenia 15 | 1,160
interstitial lung disease 15 | 298
spina bifida 15 | 1,074
Anemia 14 | 365
Endometriosis 14 | 540
Melanoma 14 | 711
Waldenstrons macroglobulinemia 14 | 765
aldosterone-producing adenoma 14 | 665
mucosa-associated lymphoid tissue lymphoma 14 | 484
Arthritis 13 | 290
fibroadenoma 13 | 559
non primary Sjogren syndrome sicca 13 | 891
Hypertension 12 | 396
Liver disease 12 | 237
Neoplasm Invasiveness 12 | 161
Prostatic Neoplasms 12 | 495
progressive supranuclear palsy 12 | 676
Stomach Neoplasms 11 | 300
Carcinoma, Hepatocellular 10 | 228
Hypertensive disease 10 | 292
Liver carcinoma 10 | 240
Lung Neoplasms 10 | 232
Neoplasm Metastasis 10 | 168
Thrombocytopenia 10 | 197
head and neck cancer 10 | 271
limb girdle muscular dystrophy 2A 10 | 213
medulloblastoma 10 | 720
posterior fossa group A ependymoma 10 | 468
sonic hedgehog group medulloblastoma 10 | 467
urothelial carcinoma 10 | 318

Tissue

Blood and immune system 186 | 16,909
Endocrine System 186 | 18,159
Female tissues 186 | 17,400
Nervous System 186 | 16,725
Respiratory system 186 | 16,393
Urinary Tract 186 | 16,678
Digestive Tract 185 | 17,369
Liver and Pancreas 185 | 16,750
Male tissues 185 | 17,142
Skin and soft tissues 185 | 17,230
Cardiovascular System 183 | 15,192

Target Family

Non-IDG 143 | 12,091
Enzyme 24 | 4,145
Kinase 8 | 634
GPCR 7 | 408
Transporter 7 | 473
Ion Channel 3 | 344

CSPA Cell Line

HCC4012 192 | 192
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Post-GPI attachment to proteins factor 6 TMEM8A Tdark Non-IDG -0.56820 3.55 16
Protocadherin gamma-B7 PCDHGB7 Tdark Non-IDG -1.62113 42.6 4
Trophoblast glycoprotein TPBG Tbio Non-IDG -2.10560 136.9 206
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Collagen alpha-2(V) chain COL5A2 Tbio Non-IDG -1.69982 44.6 96
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Aminopeptidase N ANPEP Tchem Enzyme -3.28127 1843.4 1222
Discoidin, CUB and LCCL domain-containing protein 2 DCBLD2 Tbio Non-IDG -1.08601 14.5 196