Development Level

Tbio 121 | 10,625
Tchem 38 | 1,890
Tdark 20 | 7,003
Tclin 13 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 3 | 24
GPCR: IDG Consortium (Targets) 2 | 128

IMPC Phenotype

abnormal behavior 5 | 226
preweaning lethality, complete... 5 | 633
decreased eosinophil cell numb... 3 | 41
decreased total body fat amoun... 3 | 186
enlarged spleen 3 | 26
preweaning lethality, incomple... 3 | 260
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
abnormal limb bud morphology 2 | 15
cardiovascular system phenotyp... 2 | 35
decreased bone mineral content 2 | 157
decreased circulating calcium ... 2 | 33
decreased lean body mass 2 | 195
decreased monocyte cell number 2 | 28
decreased rib number 2 | 59
enlarged heart 2 | 111
impaired glucose tolerance 2 | 52
increased body weight 2 | 42
increased circulating glycerol... 2 | 11
increased circulating triglyce... 2 | 24
increased erythrocyte cell num... 2 | 26
increased exploration in new e... 2 | 56
increased grip strength 2 | 83
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
tremors 2 | 34
vertebral fusion 2 | 23
abnormal QRS complex 1 | 25
abnormal anxiety-related respo... 1 | 1
abnormal cervical vertebrae mo... 1 | 4
abnormal coat-hair pigmentatio... 1 | 54
abnormal craniofacial morpholo... 1 | 12
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal ear morphology 1 | 5
abnormal eye morphology 1 | 38
abnormal facial morphology 1 | 9
abnormal gait 1 | 51
abnormal head shape 1 | 4
abnormal limb morphology 1 | 7
abnormal neural tube closure 1 | 37
abnormal pericardium morpholog... 1 | 11
abnormal response to new envir... 1 | 8
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal social-conspecific in... 1 | 3
abnormal tail morphology 1 | 17
abnormal thoracic vertebrae mo... 1 | 16
abnormal urination 1 | 2
abnormal vibrissa morphology 1 | 17
absent startle reflex 1 | 15
decreased Ly6C high monocyte n... 1 | 18
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 5
decreased caudal vertebrae num... 1 | 49
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating glycerol... 1 | 19
decreased heart rate 1 | 10
decreased lumbar vertebrae num... 1 | 62
decreased mean platelet volume 1 | 12
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
embryonic lethality prior to t... 1 | 187
enlarged lymph nodes 1 | 27
hyperactivity 1 | 108
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating thyroxin... 1 | 7
increased fasted circulating g... 1 | 68
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mean platelet volume 1 | 19
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
pallor 1 | 13
rib fusion 1 | 2
short tibia 1 | 82
straub tail 1 | 26
trunk curl 1 | 15

Disease

ovarian cancer 132 | 8,491
osteosarcoma 109 | 7,933
glioblastoma 102 | 5,572
medulloblastoma, large-cell 91 | 6,234
psoriasis 84 | 6,685
Cancer 80 | 2,346
malignant mesothelioma 76 | 3,163
atypical teratoid / rhabdoid tumor 73 | 4,369
lung carcinoma 73 | 2,844
lung cancer 72 | 4,473
pilocytic astrocytoma 71 | 3,086
invasive ductal carcinoma 68 | 2,950
ulcerative colitis 68 | 2,087
Breast cancer 66 | 3,098
pediatric high grade glioma 64 | 2,712
pancreatic cancer 62 | 2,300
lung adenocarcinoma 61 | 2,714
oligodendroglioma 61 | 2,849
intraductal papillary-mucinous adenoma (IPMA) 60 | 2,956
non-small cell lung cancer 60 | 2,798
cystic fibrosis 53 | 1,670
intraductal papillary-mucinous neoplasm (IPMN) 53 | 3,289
primary pancreatic ductal adenocarcinoma 53 | 1,271
interstitial cystitis 51 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 51 | 2,988
ependymoma 49 | 2,514
Carcinoma 48 | 2,147
subependymal giant cell astrocytoma 47 | 2,287
primitive neuroectodermal tumor 45 | 3,031
ductal carcinoma in situ 43 | 1,745
juvenile dermatomyositis 42 | 1,189
diabetes mellitus 40 | 1,663
astrocytic glioma 38 | 2,241
gastric carcinoma 35 | 832
breast carcinoma 33 | 1,614
dermatomyositis 33 | 966
group 4 medulloblastoma 33 | 1,875
Pick disease 32 | 1,893
group 3 medulloblastoma 32 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 32 | 1,795
pituitary cancer 32 | 1,972
adrenocortical carcinoma 31 | 1,427
posterior fossa group A ependymoma 31 | 1,511
astrocytoma 30 | 1,493
colon cancer 30 | 1,475
tuberculosis 30 | 1,563
Duchenne muscular dystrophy 29 | 602
acute quadriplegic myopathy 28 | 1,157
adult high grade glioma 28 | 2,148
nasopharyngeal carcinoma 28 | 1,056
sonic hedgehog group medulloblastoma 26 | 1,482
Multiple myeloma 23 | 1,327
esophageal adenocarcinoma 23 | 737
Alzheimer's disease 22 | 644
Atopic dermatitis 22 | 944
Multiple Sclerosis 21 | 498
Rheumatoid Arthritis 21 | 1,170
active Crohn's disease 21 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 20 | 499
atypical teratoid/rhabdoid tumor 19 | 1,095
medulloblastoma 19 | 1,524
acute myeloid leukemia 18 | 785
cutaneous lupus erythematosus 18 | 1,056
Down syndrome 17 | 548
posterior fossa group B ependymoma 17 | 1,530
Becker muscular dystrophy 15 | 187
Hypersensitivity reaction type II disease 15 | 235
Kidney disease 15 | 397
Mammary Neoplasms 15 | 410
interstitial lung disease 15 | 292
spina bifida 15 | 1,064
Anemia 14 | 252
Endometriosis 14 | 535
Waldenstrons macroglobulinemia 14 | 764
aldosterone-producing adenoma 14 | 664
mucosa-associated lymphoid tissue lymphoma 14 | 480
Arthritis 13 | 248
fibroadenoma 13 | 557
Prostatic Neoplasms 12 | 471
non-small cell lung carcinoma 12 | 413
progressive supranuclear palsy 12 | 674
Stomach Neoplasms 11 | 282
Vascular disease 11 | 281
non primary Sjogren syndrome sicca 11 | 840
primary Sjogren syndrome 11 | 788
Ankylosing spondylitis 10 | 138
glioblastoma multiforme 10 | 347
head and neck cancer 10 | 270
urothelial carcinoma 10 | 318
Barrett's esophagus 9 | 185
IGA Glomerulonephritis 9 | 454
Liver carcinoma 9 | 217
Mammary Neoplasms, Experimental 9 | 149
Neoplasm Invasiveness 9 | 127
Neoplasm Metastasis 9 | 138
Hypertension 8 | 293
Hypertensive disease 8 | 193
limb girdle muscular dystrophy 2A 8 | 156
nephrosclerosis 8 | 329
pancreatic carcinoma 8 | 567

Tissue

Cardiovascular System 187 | 17,957
Female tissues 187 | 18,646
Liver and Pancreas 187 | 18,135
Respiratory system 187 | 17,483
Urinary Tract 187 | 18,443
Blood and immune system 186 | 17,994
Digestive Tract 186 | 18,472
Endocrine System 186 | 18,511
Male tissues 186 | 17,968
Nervous System 186 | 18,560
Skin and soft tissues 185 | 18,114

Target Family

Non-IDG 143 | 11,969
Enzyme 24 | 4,146
Kinase 8 | 634
GPCR 7 | 408
Transporter 7 | 473
Ion Channel 3 | 341

CSPA Cell Line

HCC4012 192 | 192
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit beta-3 ATP1B3 Tclin Transporter -1.08214 10.9 189
Alpha-2-macroglobulin A2M Tbio Non-IDG -2.95602 802.7 553
Collagen alpha-1(I) chain COL1A1 Tbio Non-IDG -2.94271 807.7 451
Endothelial protein C receptor PROCR Tbio Non-IDG -2.67797 519.6 324
Receptor-type tyrosine-protein phosphatase mu PTPRM Tbio Enzyme -1.82872 68.8 135
Dipeptidyl peptidase 4 DPP4 Tclin Enzyme -3.60140 4091.0 900
Protocadherin gamma-C3 PCDHGC3 Tdark Non-IDG -0.62127 4.40 173
Transmembrane emp24 domain-containing protein 9 TMED9 Tdark Non-IDG -0.03714 0.58 101
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 ST3GAL1 Tchem Enzyme -1.78287 60.2 45
Membrane cofactor protein CD46 Tbio Non-IDG -2.92514 849.0 564