Development Level

Tbio 118 | 11,445
Tchem 24 | 1,598
Tclin 20 | 613
Tdark 9 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal seminal vesicle morph... 5 | 114
enlarged heart 5 | 210
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
decreased total body fat amoun... 4 | 207
decreased vertical activity 4 | 208
increased bone mineral content 4 | 108
abnormal coat appearance 3 | 31
abnormal gait 3 | 69
decreased startle reflex 3 | 75
enlarged spleen 3 | 41
abnormal bone structure 2 | 187
abnormal ear morphology 2 | 9
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
cardiovascular system phenotyp... 2 | 36
decreased cardiac muscle contr... 2 | 11
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
decreased heart rate 2 | 18
decreased lymphocyte cell numb... 2 | 83
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased circulating choleste... 2 | 66
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
preweaning lethality, complete... 2 | 979
abnormal coat-hair pigmentatio... 1 | 64
abnormal epididymis morphology 1 | 42
abnormal liver morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal snout morphology 1 | 23
abnormal urination 1 | 1
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent startle reflex 1 | 24
absent testes 1 | 6
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased monocyte cell number 1 | 8
decreased prepulse inhibition 1 | 82
dilated heart left ventricle 1 | 11
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged seminal vesicle 1 | 10
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
increased aggression 1 | 4
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased circulating thyroxin... 1 | 7
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
small superior vagus ganglion 1 | 74
thick ventricular wall 1 | 7
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 118 | 11,493
ovarian cancer 107 | 8,520
osteosarcoma 103 | 7,950
glioblastoma 77 | 5,792
psoriasis 75 | 6,694
lung cancer 72 | 4,740
Cancer 68 | 2,499
medulloblastoma, large-cell 68 | 6,241
lung carcinoma 60 | 2,843
ependymoma 58 | 4,679
interstitial cystitis 58 | 2,312
atypical teratoid / rhabdoid tumor 57 | 5,112
malignant mesothelioma 52 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 50 | 3,291
invasive ductal carcinoma 50 | 2,951
Breast cancer 49 | 3,578
non-small cell lung cancer 47 | 2,890
lung adenocarcinoma 46 | 2,716
Astrocytoma, Pilocytic 45 | 3,081
pancreatic cancer 45 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,989
group 3 medulloblastoma 43 | 4,104
adult high grade glioma 42 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 41 | 2,955
subependymal giant cell astrocytoma 41 | 2,287
tuberculosis 39 | 2,010
ulcerative colitis 38 | 1,819
oligodendroglioma 36 | 2,850
diabetes mellitus 35 | 1,728
cutaneous lupus erythematosus 33 | 1,057
Kidney cancer 31 | 2,613
juvenile dermatomyositis 31 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,962
Rheumatoid arthritis 30 | 1,191
Multiple myeloma 29 | 1,332
astrocytic glioma 28 | 2,597
primitive neuroectodermal tumor 28 | 3,035
ductal carcinoma in situ 27 | 1,745
dermatomyositis 26 | 966
primary Sjogren syndrome 25 | 735
Multiple Sclerosis 24 | 540
nasopharyngeal carcinoma 24 | 1,058
Autosomal recessive predisposition 23 | 1,442
Pick disease 23 | 1,894
esophageal adenocarcinoma 23 | 737
pituitary cancer 23 | 1,972
primary pancreatic ductal adenocarcinoma 23 | 1,109
Down syndrome 22 | 499
Hypersensitivity reaction type II disease 22 | 253
breast carcinoma 22 | 1,638
cystic fibrosis 22 | 1,696
acute quadriplegic myopathy 21 | 1,158
astrocytoma 21 | 1,146
group 4 medulloblastoma 21 | 1,855
Liver Cirrhosis, Experimental 20 | 769
Schizophrenia 20 | 1,160
Duchenne muscular dystrophy 19 | 601
Waldenstrons macroglobulinemia 18 | 765
adrenocortical carcinoma 18 | 1,428
pediatric high grade glioma 18 | 1,064
active Crohn's disease 17 | 922
periodontitis 17 | 293
active ulcerative colitis 15 | 764
Atherosclerosis 14 | 291
Atopic dermatitis 14 | 952
colon cancer 14 | 1,478
gastric carcinoma 14 | 807
Alzheimer's disease 13 | 658
Breast Neoplasms 13 | 445
Vascular disease 13 | 319
acute myeloid leukemia 13 | 783
mucosa-associated lymphoid tissue lymphoma 13 | 484
Arthritis 12 | 290
Asthma 12 | 385
Kidney disease 12 | 430
Mammary Neoplasms 12 | 425
progressive supranuclear palsy 12 | 676
sarcoidosis 12 | 370
Anemia 11 | 365
Coronary artery disease 11 | 268
Human immunodeficiency virus infectious disease 11 | 138
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
non primary Sjogren syndrome sicca 11 | 891
Bipolar Disorder 10 | 666
Chronic Lymphocytic Leukemia 10 | 262
Inflammatory bowel disease 10 | 151
Neurodegenerative disease 10 | 414
pancreatic carcinoma 10 | 562
posterior fossa group A ependymoma 10 | 468
spina bifida 10 | 1,074
Endometriosis 9 | 540
Hepatitis B 9 | 108
Hypertension 9 | 396
chronic rhinosinusitis 9 | 512
fibroadenoma 9 | 559
Allergic hypersensitivity disease 8 | 126
Splenomegaly 8 | 190
aldosterone-producing adenoma 8 | 665
hepatocellular carcinoma 8 | 547
nephrosclerosis 8 | 333

Tissue

Blood and immune system 162 | 16,909
Digestive Tract 162 | 17,369
Endocrine System 162 | 18,159
Female tissues 162 | 17,400
Respiratory system 162 | 16,393
Skin and soft tissues 162 | 17,230
Liver and Pancreas 161 | 16,750
Male tissues 161 | 17,142
Urinary Tract 161 | 16,678
Cardiovascular System 157 | 15,192
Nervous System 156 | 16,725

Target Family

Non-IDG 126 | 12,091
Transporter 18 | 473
Enzyme 16 | 4,145
GPCR 6 | 408
Kinase 3 | 634
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

CSPA Cell Line

HBL-1 171 | 171
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Mucin-16 MUC16 Tbio Non-IDG -2.09951 138.4 0
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Zinc transporter ZIP10 SLC39A10 Tbio Transporter -1.20558 16.3 102
Proton-coupled folate transporter SLC46A1 Tchem Transporter -2.23182 177.1 76
Ephrin type-B receptor 1 EPHB1 Tchem Kinase -1.70013 52.0 389
Transmembrane 9 superfamily member 3 TM9SF3 Tdark Non-IDG -1.62419 41.9 40
UL-16 binding protein 5 RAET1G Tbio Non-IDG -0.77225 5.67 20