Development Level

Tbio 122 | 11,445
Tchem 25 | 1,598
Tclin 15 | 613
Tdark 5 | 6,588

Collection

GPCR: IDG Consortium (Targets) 3 | 126
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, incomple... 7 | 499
abnormal behavior 6 | 298
decreased total body fat amoun... 4 | 207
enlarged heart 4 | 210
increased bone mineral content 4 | 108
increased heart weight 4 | 62
preweaning lethality, complete... 4 | 979
abnormal retina morphology 3 | 71
abnormal seminal vesicle morph... 3 | 114
hypoactivity 3 | 132
improved glucose tolerance 3 | 79
increased mean corpuscular vol... 3 | 92
tremors 3 | 39
abnormal coat appearance 2 | 31
abnormal coat-hair pigmentatio... 2 | 64
abnormal ear morphology 2 | 9
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal lens morphology 2 | 81
abnormal tooth morphology 2 | 24
cataract 2 | 92
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating aspartat... 2 | 34
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
decreased eosinophil cell numb... 2 | 24
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
decreased vertical activity 2 | 208
dilated heart left ventricle 2 | 11
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased circulating triglyce... 2 | 42
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 47
persistence of hyaloid vascula... 2 | 33
polycystic kidney 2 | 15
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal incisor morphology 1 | 4
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal radius morphology 1 | 8
abnormal response to new envir... 1 | 10
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal ulna morphology 1 | 8
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
absent testes 1 | 6
absent vibrissae 1 | 12
decreased cardiac muscle contr... 1 | 11
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
enlarged adrenal glands 1 | 3
enlarged epididymis 1 | 31
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydrometra 1 | 53
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total retina thickne... 1 | 4
irregularly shaped pupil 1 | 7
short tibia 1 | 97
trunk curl 1 | 16

Disease

Carcinoma 136 | 11,493
ovarian cancer 111 | 8,520
glioblastoma 92 | 5,792
osteosarcoma 87 | 7,950
Cancer 83 | 2,499
medulloblastoma, large-cell 77 | 6,241
atypical teratoid / rhabdoid tumor 76 | 5,112
psoriasis 73 | 6,694
lung cancer 72 | 4,740
pancreatic cancer 71 | 2,398
lung carcinoma 70 | 2,843
Breast cancer 67 | 3,578
malignant mesothelioma 66 | 3,232
ependymoma 65 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 63 | 2,955
lung adenocarcinoma 63 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 61 | 3,291
non-small cell lung cancer 60 | 2,890
group 3 medulloblastoma 58 | 4,104
invasive ductal carcinoma 58 | 2,951
Astrocytoma, Pilocytic 54 | 3,081
interstitial cystitis 54 | 2,312
adult high grade glioma 52 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 52 | 2,989
cystic fibrosis 45 | 1,696
primitive neuroectodermal tumor 45 | 3,035
ulcerative colitis 44 | 1,819
pancreatic ductal adenocarcinoma liver metastasis 43 | 1,962
tuberculosis 43 | 2,010
Kidney cancer 41 | 2,613
ductal carcinoma in situ 41 | 1,745
oligodendroglioma 41 | 2,850
subependymal giant cell astrocytoma 40 | 2,287
esophageal adenocarcinoma 35 | 737
diabetes mellitus 34 | 1,728
juvenile dermatomyositis 34 | 1,187
primary pancreatic ductal adenocarcinoma 33 | 1,109
breast carcinoma 32 | 1,638
pituitary cancer 32 | 1,972
astrocytic glioma 31 | 2,597
colon cancer 30 | 1,478
nasopharyngeal carcinoma 30 | 1,058
Autosomal recessive predisposition 29 | 1,442
gastric carcinoma 29 | 807
Duchenne muscular dystrophy 28 | 601
dermatomyositis 26 | 966
Rheumatoid arthritis 25 | 1,191
acute quadriplegic myopathy 23 | 1,158
adrenocortical carcinoma 23 | 1,428
Liver Cirrhosis, Experimental 22 | 769
Pick disease 22 | 1,894
active ulcerative colitis 22 | 764
Kidney disease 21 | 430
astrocytoma 21 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 21 | 510
Multiple Sclerosis 20 | 540
group 4 medulloblastoma 20 | 1,855
pediatric high grade glioma 20 | 1,064
spina bifida 20 | 1,074
Atopic dermatitis 19 | 952
cutaneous lupus erythematosus 19 | 1,057
Alzheimer's disease 18 | 658
Barrett's esophagus 17 | 182
Breast Neoplasms 17 | 445
Schizophrenia 17 | 1,160
Anemia 16 | 365
Liver disease 16 | 237
Mammary Neoplasms 16 | 425
active Crohn's disease 16 | 922
interstitial lung disease 16 | 298
Down syndrome 15 | 499
Endometriosis 15 | 540
Hypersensitivity reaction type II disease 15 | 253
Melanoma 15 | 711
Vascular disease 15 | 319
posterior fossa group A ependymoma 15 | 468
Multiple myeloma 14 | 1,332
Prostatic Neoplasms 14 | 495
mucosa-associated lymphoid tissue lymphoma 14 | 484
non-small cell lung carcinoma 14 | 317
Hypertension 13 | 396
Neoplasm Metastasis 13 | 168
Atherosclerosis 12 | 291
Liver Cirrhosis 12 | 181
Stomach Neoplasms 12 | 300
acute myeloid leukemia 12 | 783
fibroadenoma 12 | 559
head and neck cancer 12 | 271
non primary Sjogren syndrome sicca 12 | 891
Arthritis 11 | 290
Becker muscular dystrophy 11 | 191
Coronary artery disease 11 | 268
Liver cancer 11 | 604
Liver carcinoma 11 | 240
Lung Neoplasms 11 | 232
Thrombocytopenia 11 | 197
aldosterone-producing adenoma 11 | 665
Obesity 10 | 678
chronic rhinosinusitis 10 | 512
primary Sjogren syndrome 10 | 735

Tissue

Endocrine System 159 | 18,159
Urinary Tract 159 | 16,678
Digestive Tract 158 | 17,369
Female tissues 158 | 17,400
Liver and Pancreas 158 | 16,750
Male tissues 158 | 17,142
Respiratory system 158 | 16,393
Skin and soft tissues 158 | 17,230
Blood and immune system 157 | 16,909
Nervous System 157 | 16,725
Cardiovascular System 153 | 15,192

Target Family

Non-IDG 111 | 12,091
Enzyme 19 | 4,145
Transporter 14 | 473
Kinase 12 | 634
GPCR 7 | 408
Ion Channel 2 | 344
Transcription Factor 2 | 1,400

CSPA Cell Line

CaLu3 167 | 167
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.90516 156.1 254
G-protein coupled receptor 39 GPR39 Tchem GPCR -1.77076 66.5 232
Trophoblast glycoprotein TPBG Tbio Non-IDG -2.10560 136.9 206
CD276 antigen CD276 Tbio Non-IDG -3.03140 785.5 481
Solute carrier organic anion transporter family member 3A1 SLCO3A1 Tbio Transporter -1.39614 24.1 46
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Zinc transporter ZIP6 SLC39A6 Tbio Transporter -1.66663 50.0 172