Development Level

Tbio 80 | 11,445
Tchem 21 | 1,598
Tclin 10 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

abnormal behavior 5 | 298
decreased total body fat amoun... 4 | 207
decreased vertical activity 3 | 208
increased bone mineral content 3 | 108
increased heart weight 3 | 62
preweaning lethality, incomple... 3 | 499
abnormal eye morphology 2 | 68
decreased body length 2 | 101
decreased cardiac muscle contr... 2 | 11
dilated heart left ventricle 2 | 11
enlarged heart 2 | 210
enlarged spleen 2 | 41
improved glucose tolerance 2 | 79
increased circulating choleste... 2 | 66
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
preweaning lethality, complete... 2 | 979
tremors 2 | 39
abnormal anxiety-related respo... 1 | 1
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal limb bud morphology 1 | 17
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
abnormal social-conspecific in... 1 | 3
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal tail movements 1 | 12
abnormal urinary bladder morph... 1 | 11
abnormal urination 1 | 1
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased monocyte cell number 1 | 8
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thrombocytopenia 1 | 56

Disease

Carcinoma 93 | 11,493
ovarian cancer 75 | 8,520
glioblastoma 64 | 5,792
osteosarcoma 60 | 7,950
Cancer 56 | 2,499
lung cancer 54 | 4,740
atypical teratoid / rhabdoid tumor 53 | 5,112
malignant mesothelioma 50 | 3,232
psoriasis 50 | 6,694
ependymoma 49 | 4,679
medulloblastoma, large-cell 49 | 6,241
Breast cancer 46 | 3,578
lung carcinoma 45 | 2,843
Astrocytoma, Pilocytic 44 | 3,081
pancreatic cancer 44 | 2,398
invasive ductal carcinoma 42 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 41 | 2,955
adult high grade glioma 40 | 3,801
non-small cell lung cancer 39 | 2,890
ulcerative colitis 39 | 1,819
intraductal papillary-mucinous carcinoma (IPMC) 36 | 2,989
cystic fibrosis 35 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 35 | 3,291
lung adenocarcinoma 34 | 2,716
primitive neuroectodermal tumor 34 | 3,035
ductal carcinoma in situ 32 | 1,745
group 3 medulloblastoma 32 | 4,104
interstitial cystitis 32 | 2,312
Kidney cancer 31 | 2,613
oligodendroglioma 31 | 2,850
subependymal giant cell astrocytoma 30 | 2,287
gastric carcinoma 28 | 807
primary pancreatic ductal adenocarcinoma 27 | 1,109
tuberculosis 27 | 2,010
diabetes mellitus 26 | 1,728
adrenocortical carcinoma 24 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
juvenile dermatomyositis 23 | 1,187
pituitary cancer 23 | 1,972
astrocytic glioma 22 | 2,597
colon cancer 21 | 1,478
nasopharyngeal carcinoma 21 | 1,058
breast carcinoma 20 | 1,638
group 4 medulloblastoma 20 | 1,855
Rheumatoid arthritis 19 | 1,191
Duchenne muscular dystrophy 18 | 601
acute quadriplegic myopathy 18 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 510
Liver Cirrhosis, Experimental 15 | 769
Multiple Sclerosis 15 | 540
active Crohn's disease 15 | 922
cutaneous lupus erythematosus 15 | 1,057
dermatomyositis 15 | 966
esophageal adenocarcinoma 15 | 737
Autosomal recessive predisposition 14 | 1,442
Breast Neoplasms 14 | 445
Kidney disease 14 | 430
pediatric high grade glioma 14 | 1,064
Atopic dermatitis 13 | 952
Hypersensitivity reaction type II disease 13 | 253
Hypertension 13 | 396
Mammary Neoplasms 13 | 425
Schizophrenia 13 | 1,160
Vascular disease 13 | 319
active ulcerative colitis 13 | 764
astrocytoma 13 | 1,146
Endometriosis 12 | 540
Pick disease 12 | 1,894
aldosterone-producing adenoma 12 | 665
urothelial carcinoma 12 | 318
Alzheimer's disease 11 | 658
Atherosclerosis 11 | 291
Coronary artery disease 11 | 268
posterior fossa group A ependymoma 11 | 468
Becker muscular dystrophy 10 | 191
Cerebrovascular disease 10 | 238
Melanoma 10 | 711
Prostatic Neoplasms 10 | 495
fibroadenoma 10 | 559
Arthritis 9 | 290
Hypertensive disease 9 | 292
Neoplasm Invasiveness 9 | 161
Skin cancer 9 | 469
acute myeloid leukemia 9 | 783
interstitial lung disease 9 | 298
limb girdle muscular dystrophy 2A 9 | 213
mucosa-associated lymphoid tissue lymphoma 9 | 484
non primary Sjogren syndrome sicca 9 | 891
non-small cell lung carcinoma 9 | 317
Anemia 8 | 365
Barrett's esophagus 8 | 182
Carcinoma, Hepatocellular 8 | 228
Liver carcinoma 8 | 240
Liver disease 8 | 237
Mental Depression 8 | 333
Multiple myeloma 8 | 1,332
Neoplasm Metastasis 8 | 168
Stomach Neoplasms 8 | 300
Waldenstrons macroglobulinemia 8 | 765
sonic hedgehog group medulloblastoma 7 | 467

Tissue

Endocrine System 107 | 18,159
Female tissues 107 | 17,400
Nervous System 107 | 16,725
Respiratory system 107 | 16,393
Urinary Tract 107 | 16,678
Digestive Tract 106 | 17,369
Liver and Pancreas 106 | 16,750
Male tissues 106 | 17,142
Skin and soft tissues 106 | 17,230
Blood and immune system 105 | 16,909
Cardiovascular System 104 | 15,192

Target Family

Non-IDG 76 | 12,091
Enzyme 16 | 4,145
Transporter 10 | 473
Ion Channel 4 | 344
Kinase 4 | 634
GPCR 2 | 408

CSPA Cell Line

786-O 112 | 112
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Protein HEG homolog 1 HEG1 Tbio Non-IDG -2.11308 129.3 11
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Trophoblast glycoprotein TPBG Tbio Non-IDG -2.10560 136.9 206
UL-16 binding protein 5 RAET1G Tbio Non-IDG -0.77225 5.67 20
CD276 antigen CD276 Tbio Non-IDG -3.03140 785.5 481
Zinc transporter ZIP6 SLC39A6 Tbio Transporter -1.66663 50.0 172
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378