Tdark Zinc finger protein 511

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May be involved in transcriptional regulation.

Property Summary

NCBI Gene PubMed Count	6
PubMed Score	0.58

PubTator Score	0.50

Knowledge Summary

Patent

No data available

TINX Plot

Disease (1)

Expression Atlas

Disease	Target Count	P-value
ovarian cancer	8520	1.7e-05

Expression

Specificity
Differential

Differential Expression (1)

Disease	log2 FC	p
ovarian cancer	1.100	1.7e-05

Uterus 17,618

Ovary 17,971

Colon - Sigmoid 18,089

Vagina 17,834

Esophagus - Muscularis 18,017

Esophagus - Gastroesophageal Junction 18,000

Prostate 18,213

Thyroid 18,024

Nerve - Tibial 18,007

Artery - Coronary 17,949

Spleen 17,614

Testis 18,518

Cells - EBV-transformed lymphocytes 18,186

Artery - Aorta 17,896

Brain - Cerebellum 17,983

Brain - Cerebellar Hemisphere 18,015

Pituitary 18,147

Adrenal Gland 18,071

Adipose - Visceral (Omentum) 17,937

Small Intestine - Terminal Ileum 17,954

Lung 18,057

Cells - Transformed fibroblasts 17,577

Breast - Mammary Tissue 18,103

Artery - Tibial 17,631

Liver 18,071

Stomach 17,879

Adipose - Subcutaneous 18,110

Esophagus - Mucosa 18,076

Muscle - Skeletal 17,778

Heart - Atrial Appendage 17,896

Colon - Transverse 17,825

Minor Salivary Gland 18,005

Skin - Not Sun Exposed (Suprapubic) 18,081

Skin - Sun Exposed (Lower leg) 17,968

Brain - Frontal Cortex (BA9) 18,069

Brain - Cortex 18,039

Brain - Spinal cord (cervical c-1) 17,973

Brain - Nucleus accumbens (basal ganglia... 18,024

Brain - Caudate (basal ganglia) 18,001

Heart - Left Ventricle 18,006

Brain - Anterior cingulate cortex (BA24) 17,989

Kidney - Cortex 17,329

Brain - Amygdala 18,006

Brain - Hypothalamus 18,169

Brain - Putamen (basal ganglia) 17,863

Brain - Hippocampus 18,011

Whole Blood 17,439

Brain - Substantia nigra 17,981

Pancreas 18,123

Adult Testis 10,836

CD8 Cells 9,840

Fetal Liver 8,402

Fetal Ovary 9,118

Fetal Testis 7,955

Gall bladder

Gut

Liver

Monocyte

Ovary

Testis

BTO:0004410

adipose tissue 15,837

adrenal gland 15,963

appendix 16,247

bone marrow 14,571

breast 16,063

cerebral cortex 16,630

cervix, uterine 15,871

colon 15,959

duodenum 15,975

endometrium 16,349

epididymis 15,863

esophagus 15,898

fallopian tube 16,245

gallbladder 16,333

heart muscle 14,972

kidney 15,917

liver 14,587

lung 16,312

lymph node 15,833

ovary 15,408

pancreas 14,070

parathyroid gland 14,769

placenta 15,937

prostate 16,460

rectum 15,705

salivary gland 14,981

seminal vesicle 15,918

skeletal muscle 14,011

skin 16,206

small intestine 16,154

smooth muscle 15,857

spleen 15,972

stomach 16,099

testis 17,936

thyroid gland 15,959

tonsil 15,400

urinary bladder 15,814

Liver and Pancreas 16,750

Digestive Tract 17,369

Urinary Tract 16,678

Endocrine System 18,159

Blood and immune system 16,909

Respiratory system 16,393

Female tissues 17,400

Male tissues 17,142

Skin and soft tissues 17,230

Nervous System 16,725

Cardiovascular System 15,192

Brain 7,346

Chondrocyte 20

Colonic cancer cell 562

Testis 3,897

Uterine cervix 418

See source...

Alveolar macrophage 10

See source...

Synonym

Accession	Q8NB15 A8K8L5 Q8WUP1 Q96BV2
Symbols

Gene

ZNF511

Ortholog (10)

Species	Source	Disease
Pig 10,168	Inparanoid OMA EggNOG
Opossum 12,230	Inparanoid OMA EggNOG
Dog 15,073	Inparanoid OMA EggNOG
Cow 15,320	Inparanoid OMA EggNOG
Chicken 7,827	OMA EggNOG
Zebrafish 9,726	Inparanoid OMA
Mouse 16,570	Inparanoid OMA EggNOG
Rat 15,117	Inparanoid OMA EggNOG
Chimp 14,140	Inparanoid OMA EggNOG
Macaque 12,761	Inparanoid OMA EggNOG

UniProt Keyword (12)

Complete proteome 20,231

DNA-binding 2,008

Metal-binding 3,672

Nucleus 5,259

Reference proteome 20,231

Repeat 4,916

Transcription 2,402

Transcription regulation 2,336

Zinc 2,356

Zinc-finger 1,785

See all...

GO Function (2)

DNA binding 1,481

metal ion binding 2,256

GO Component (1)

nucleus 5,097

GO Process (2)

regulation of transcription, DNA-templat... 1,135

transcription, DNA-templated 1,742

Compartment GO Term (10)

Cell 16,178

Cell part 16,177

Intracellular 14,109

Intracellular membrane-bounded organelle 10,341

Intracellular organelle 12,025

Intracellular part 13,972

Nucleus 7,562

Organelle 12,238

cellular_component 18,320

membrane-bounded organelle 11,132

HCA RNA Cell Line (56)

A-431 16,131

A549 15,174

AF22 16,160

AN3-CA 15,648

ASC TERT1 14,842

BEWO 16,726

BJ 15,448

BJ hTERT+ 15,353

BJ hTERT+ SV40 Large T+ 15,609

BJ hTERT+ SV40 Large T+ RasG12V 15,493

See all...

Protein-protein Interaction (10)

NCKAP1 KLHL15 CYFIP2 CYFIP1 RAD50 WASF2 ABI2 ABI1 TMCO6 WASF1

AA Sequence

MQLPPALCARLAAGPGAAEPLPVERDPAAGAAPFRFVARPVRFPREHQFFEDGDVQRHLYLQDVIMQVAD      1 - 70
VPEKPRVPAFACQVAGCCQVFDALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSER     71 - 140
QDMYQCLVEGCTEKFKTSRDRKDHMVRMHLYPADFRFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEP    141 - 210
VAASPAPAGERRIYRHRSVSELFLKPVLNMCSVLRILGCTWAAALLILNSER                      211 - 262
//

Text Mined References (7)

Summary
Details

	PMID	Year	Title