| Disease | Target Count | P-value |
|---|---|---|
| non-small cell lung cancer | 2890 | 1.1e-24 |
| lung carcinoma | 2843 | 4.0e-20 |
| psoriasis | 6694 | 3.7e-15 |
| glioblastoma | 5792 | 1.1e-08 |
| ovarian cancer | 8520 | 4.0e-08 |
| lung adenocarcinoma | 2716 | 7.9e-08 |
| primitive neuroectodermal tumor | 3035 | 2.7e-05 |
| pituitary cancer | 1972 | 5.6e-04 |
| adult high grade glioma | 3801 | 9.1e-04 |
| Astrocytoma, Pilocytic | 3081 | 1.4e-03 |
| subependymal giant cell astrocytoma | 2287 | 1.4e-03 |
| interstitial cystitis | 2312 | 4.3e-03 |
| astrocytic glioma | 2597 | 6.4e-03 |
| gastric carcinoma | 807 | 8.0e-03 |
| ependymoma | 4679 | 8.7e-03 |
| Pick disease | 1894 | 1.0e-02 |
| oligodendroglioma | 2850 | 1.4e-02 |
| medulloblastoma, large-cell | 6241 | 1.5e-02 |
| group 4 medulloblastoma | 1855 | 2.2e-02 |
| aldosterone-producing adenoma | 665 | 2.7e-02 |
| osteosarcoma | 7950 | 3.2e-02 |
| invasive ductal carcinoma | 2951 | 4.0e-02 |
| atypical teratoid / rhabdoid tumor | 5112 | 4.8e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| CHARGE syndrome | 26 | 3.138 | 1.6 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -2.900 | 9.1e-04 |
| aldosterone-producing adenoma | -1.370 | 2.7e-02 |
| astrocytic glioma | -2.800 | 6.4e-03 |
| Astrocytoma, Pilocytic | -2.500 | 1.4e-03 |
| atypical teratoid / rhabdoid tumor | -1.800 | 4.8e-02 |
| ependymoma | -3.200 | 8.7e-03 |
| gastric carcinoma | -3.500 | 8.0e-03 |
| glioblastoma | -3.200 | 1.1e-08 |
| group 4 medulloblastoma | -2.500 | 2.2e-02 |
| interstitial cystitis | -1.200 | 4.3e-03 |
| invasive ductal carcinoma | -1.100 | 4.0e-02 |
| lung adenocarcinoma | -1.500 | 7.9e-08 |
| lung carcinoma | -2.500 | 4.0e-20 |
| medulloblastoma, large-cell | -2.700 | 1.5e-02 |
| non-small cell lung cancer | -3.344 | 1.1e-24 |
| oligodendroglioma | -2.600 | 1.4e-02 |
| osteosarcoma | 2.128 | 3.2e-02 |
| ovarian cancer | -1.300 | 4.0e-08 |
| Pick disease | -1.300 | 1.0e-02 |
| pituitary cancer | 1.300 | 5.6e-04 |
| primitive neuroectodermal tumor | -3.700 | 2.7e-05 |
| psoriasis | -1.200 | 3.7e-15 |
| subependymal giant cell astrocytoma | -3.594 | 1.4e-03 |
| Species | Source | Disease |
|---|---|---|
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA | ||
| Inparanoid OMA | ||
| OMA EggNOG | ||
| Inparanoid OMA | ||
| Inparanoid OMA |
MNMANFLRGFEEKGIKNDRPEDQLSKEKKKILFSFCEVCNIQLNSAAQAQVHSNGKSHRKRVKQLSDGQP 1 - 70 PPPAQASPSSNSSTGSTCHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDSSSAVGLFPNFNTMDPVQKAV 71 - 140 INHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALDATKNKPKMVPSKDSAKANPSC 141 - 210 SITPITGNNSDKSEDKGKLKASSSSQPSSSESGSFLLKSGTTPLPPGAATSPSKSTNGAPGTVVESEEEK 211 - 280 AKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKMQNGSKGSGLQNKTFHC 281 - 350 EICDVHVNSEIQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDMMKPLAPAFLSSP 351 - 420 LAAAAAVSSALSLPPRPSASLFQAPAIPPALLRPGHGPIRATPASILFAPY 421 - 471 //
