| Tbio | Zinc finger protein 33B |
May be involved in transcriptional regulation.
This gene encodes a member of the zinc finger family of proteins. This gene shows decreased expression in cumulus cells derived from patients undergoing controlled ovarian stimulation. This gene is present in a gene cluster with several related zinc finger genes in the pericentromeric region of chromosome 10. Pseudogenes have been identified on chromosomes 7 and 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
This gene encodes a member of the zinc finger family of proteins. This gene shows decreased expression in cumulus cells derived from patients undergoing controlled ovarian stimulation. This gene is present in a gene cluster with several related zinc finger genes in the pericentromeric region of chromosome 10. Pseudogenes have been identified on chromosomes 7 and 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| Breast cancer | 3578 | 1.6e-22 |
| osteosarcoma | 7950 | 2.9e-07 |
| atypical teratoid / rhabdoid tumor | 5112 | 7.8e-07 |
| group 4 medulloblastoma | 1855 | 1.4e-06 |
| malignant mesothelioma | 3232 | 3.3e-06 |
| ovarian cancer | 8520 | 1.4e-04 |
| cystic fibrosis | 1696 | 2.0e-04 |
| interstitial cystitis | 2312 | 2.8e-04 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 4.8e-03 |
| lung cancer | 4740 | 1.6e-02 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 2.4e-02 |
| medulloblastoma, large-cell | 6241 | 2.9e-02 |
| spina bifida | 1074 | 4.6e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Multiple endocrine neoplasia type 2B | 17 | 4.03 | 2.0 |
| Multiple endocrine neoplasia type 2A | 20 | 3.686 | 1.8 |
| Disease | log2 FC | p |
|---|---|---|
| atypical teratoid / rhabdoid tumor | 1.600 | 7.8e-07 |
| Breast cancer | -1.500 | 1.6e-22 |
| cystic fibrosis | -1.300 | 2.0e-04 |
| group 4 medulloblastoma | 1.600 | 1.4e-06 |
| interstitial cystitis | -1.100 | 2.8e-04 |
| intraductal papillary-mucinous carcinoma... | -1.200 | 2.4e-02 |
| intraductal papillary-mucinous neoplasm ... | -1.500 | 4.8e-03 |
| lung cancer | 1.100 | 1.6e-02 |
| malignant mesothelioma | -2.200 | 3.3e-06 |
| medulloblastoma, large-cell | 1.600 | 2.9e-02 |
| osteosarcoma | -1.586 | 2.9e-07 |
| ovarian cancer | -1.300 | 1.4e-04 |
| spina bifida | -1.287 | 4.6e-02 |
MNKVDQKFQGSVSFKDVTVGFTQEEWQHLDPSQRALYRDVMLENYSNLVSVGYCAHKPEVIFRLEQGEEP 1 - 70 WRLEEEFPSQSFPEVWTADHLKERSQENQSKHLWEVVFINNEMLTKEQGNVIGIPFNMDVSSFPSRKMFC 71 - 140 QYDSRGMSFNTVSELVISKINYLGKKSDEFNACGKLLLNIKHDETHTREKNEVLKNRNTLSHRENTLQHE 141 - 210 KIQTLDHNFEYSICQETLLEKAVFNTRKRENAEENNCDYNEFGRTFCDSSSLLFHQIPPSKDSHYEFSDC 211 - 280 EKFLCVKSTLSKHDGVPVKHYDCGESGNNFRRKLCLSQLQKGDKGEKHFECNECGKAFWEKSHLTRHQRV 281 - 350 HTGEKHFQCNQCGKTFWEKSNLTKHQRSHTGEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQCNACGK 351 - 420 TFYQKSDLTKHQRTHTGQKPYECYECGKSFCMNSHLTVHQRTHTGEKPFECLECGKSFCQKSHLTQHQRT 421 - 490 HIGDKPYECNACGKTFYHKSVLTRHQIIHTGLKPYECYECGKTFCLKSDLTIHQRTHTGEKPFACPECGK 491 - 560 FFSHKSTLSQHYRTHTGEKPYECHECGKIFYNKSYLTKHNRTHTGEKPYECNECGKTFCQKSQLTQHQRI 561 - 630 HIGEKPYECNECGKAFCHKSALIVHQRTHTQEKPYKCNECGKSFCVKSGLILHERKHTGEKPYECNECGK 631 - 700 SFSHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSDLAKHQRSHTGEKPYECNTCRKTFSQKSNLIVHQRT 701 - 770 HIGEKPYE 771 - 778 //
