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Tbio
ZNF326
DBIRD complex subunit ZNF326

Protein Summary
Description
Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. May play a role in neuronal differentiation and is able to bind DNA and activate expression in vitro.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000340281
  • ENSP00000340796
  • ENSG00000162664
  • ENST00000361911
  • ENSP00000355318

Symbol
  • ZIRD
  • ZIRD
  • ZAN75
  • Zfp326
  • dJ871E2.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.99
ligand (protein) perturbation
0.99
molecular function
0.76
virus perturbation
0.76
transcription factor binding site profile
0.74


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.19   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 133   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.19   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 133   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0