Tdark ZNF208 Zinc finger protein 208

Protein Summary

Description

May be involved in transcriptional regulation. Zinc finger proteins (ZNFs), such as ZNF208, bind DNA and, through this binding, regulate gene transcription. Most ZNFs contain conserved C2H2 motifs and are classified as Kruppel-type zinc fingers. A conserved protein motif, termed the Kruppel-associated box (KRAB) domain, mediates protein-protein interactions (Eichler et al., 1998 [PubMed 9724325]). See ZNF91 (MIM 603971) for further information on ZNFs.[supplied by OMIM, Aug 2009]

Uniprot Accession IDs

• O43345

Gene Name

• ZNF208

Ensembl ID

• ENST00000397126
• ENSP00000380315
• ENSG00000160321

Symbol

• ZNF91L
• PMIDP
• ZNF95

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell line	0.58
protein domain	0.58
tissue sample	0.47
tissue	0.44
cell type or tissue	0.42

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.7   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 3   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.7   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 3   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0