You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
ZNF197
Zinc finger protein 197

Protein Summary
Description
May be involved in transcriptional regulation. This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Naturally-occurring readthrough transcription is observed between this gene and the upstream zinc finger protein 660 gene and is represented by GeneID:110354863. [provided by RefSeq, May 2017]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000344387
  • ENSP00000345809
  • ENSG00000186448
  • ENST00000383744
  • ENSP00000373250
  • ENST00000383745
  • ENSP00000373251
  • ENST00000396058
  • ENSP00000379370
  • ENST00000627517
  • ENSP00000487305
  • ENSG00000281709
  • ENST00000627752
  • ENSP00000486777
  • ENST00000627845
  • ENSP00000486739
  • ENST00000628172
  • ENSP00000485709

Symbol
  • ZKSCAN9
  • ZNF166
  • P18
  • VHLaK
  • ZNF20
  • ZNF166
  • ZKSCAN9
  • ZSCAN41
  • D3S1363E
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
microRNA
0.72
virus perturbation
0.72
histone modification site profile
0.7
small molecule perturbation
0.57


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.03   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 114   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.03   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 114   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0