| Tdark | Zinc finger protein 195 |
May be involved in transcriptional regulation.
This gene encodes a protein belonging to the Krueppel C2H2-type zinc-finger protein family. These family members are transcription factors that are implicated in a variety of cellular processes. This gene is located near the centromeric border of chromosome 11p15.5, next to an imprinted domain that is associated with maternal-specific loss of heterozygosity in Wilms' tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
This gene encodes a protein belonging to the Krueppel C2H2-type zinc-finger protein family. These family members are transcription factors that are implicated in a variety of cellular processes. This gene is located near the centromeric border of chromosome 11p15.5, next to an imprinted domain that is associated with maternal-specific loss of heterozygosity in Wilms' tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| primitive neuroectodermal tumor | 3035 | 4.6e-07 |
| Pick disease | 1894 | 4.4e-06 |
| atypical teratoid / rhabdoid tumor | 5112 | 1.1e-05 |
| medulloblastoma, large-cell | 6241 | 1.1e-05 |
| nasopharyngeal carcinoma | 1058 | 1.5e-04 |
| group 3 medulloblastoma | 4104 | 6.3e-04 |
| lung cancer | 4740 | 9.8e-04 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 1.5e-03 |
| progressive supranuclear palsy | 676 | 5.6e-03 |
| intraductal papillary-mucinous adenoma (IPMA) | 2955 | 7.1e-03 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 2.0e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Wilson-Turner syndrome | 14 | 3.057 | 1.5 |
| Disease | log2 FC | p |
|---|---|---|
| atypical teratoid / rhabdoid tumor | 1.200 | 1.1e-05 |
| group 3 medulloblastoma | 1.400 | 6.3e-04 |
| intraductal papillary-mucinous adenoma (... | 1.300 | 7.1e-03 |
| intraductal papillary-mucinous carcinoma... | 1.600 | 1.5e-03 |
| intraductal papillary-mucinous neoplasm ... | 1.500 | 2.0e-02 |
| lung cancer | 1.700 | 9.8e-04 |
| medulloblastoma, large-cell | 1.700 | 1.1e-05 |
| nasopharyngeal carcinoma | 1.100 | 1.5e-04 |
| Pick disease | -1.400 | 4.4e-06 |
| primitive neuroectodermal tumor | 1.600 | 4.6e-07 |
| progressive supranuclear palsy | -1.300 | 5.6e-03 |
MTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEA 1 - 70 ADGHPEMGFHHATQACLELLGSSDLPASASQSAGITGVNHRAQPGLNVSVDKFTALCSPGVLQTVKWFLE 71 - 140 FRCIFSLAMSSHFTQDLLPEQGIQDAFPKRILRGYGNCGLDNLYLRKDWESLDECKLQKDYNGLNQCSST 141 - 210 THSKIFQYNKYVKIFDNFSNLHRRNISNTGEKPFKCQECGKSFQMLSFLTEHQKIHTGKKFQKCGECGKT 211 - 280 FIQCSHFTEPENIDTGEKPYKCQECNNVIKTCSVLTKNRIYAGGEHYRCEEFGKVFNQCSHLTEHEHGTE 281 - 350 EKPCKYEECSSVFISCSSLSNQQMILAGEKLSKCETWYKGFNHSPNPSKHQRNEIGGKPFKCEECDSIFK 351 - 420 WFSDLTKHKRIHTGEKPYKCDECGKAYTQSSHLSEHRRIHTGEKPYQCEECGKVFRTCSSLSNHKRTHSE 421 - 490 EKPYTCEECGNIFKQLSDLTKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEECGRVFM 491 - 560 WFSDITKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEKCGKAFTQFSHLTVHESIHT 561 - 629 //
