Protein Summary
May be involved in transcriptional regulation. This gene encodes a protein belonging to the Krueppel C2H2-type zinc-finger protein family. These family members are transcription factors that are implicated in a variety of cellular processes. This gene is located near the centromeric border of chromosome 11p15.5, next to an imprinted domain that is associated with maternal-specific loss of heterozygosity in Wilms' tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
- ENST00000005082
- ENSP00000005082
- ENSG00000005801
- ENST00000343338
- ENSP00000344483
- ENST00000354599
- ENSP00000346613
- ENST00000399602
- ENSP00000382511
- ENST00000429541
- ENSP00000387998
- ENST00000438262
- ENSP00000414353
- ENST00000526601
- ENSP00000435828
- ENST00000528218
- ENSP00000436384
- ENST00000618467
- ENSP00000482411
- ZNFP104
- HRF1
- ZNFP104
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
virus perturbation | 0.68 | ||
cell type or tissue | 0.59 | ||
protein domain | 0.58 | ||
histone modification site profile | 0.57 | ||
disease perturbation | 0.56 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 4.53 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 126 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 4.53 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 126 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0