Protein Summary
May be involved in transcriptional regulation. Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See MIM 604749 for additional information on zinc finger proteins.[supplied by OMIM, Jul 2003]
- ENST00000459757
- ENSP00000419435
- ENSG00000197841
- ENST00000492450
- ENSP00000420727
- HHZ181
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.76 | ||
virus perturbation | 0.64 | ||
tissue sample | 0.61 | ||
protein domain | 0.58 | ||
cell line | 0.56 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.18 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 49 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.18 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 49 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0