| Tdark | Zinc finger protein 160 |
May be involved in transcriptional regulation.
The protein encoded by this gene is a Kruppel-related zinc finger protein which is characterized by the presence of an N-terminal repressor domain, the Kruppel-associated box (KRAB). The KRAB domain is a potent repressor of transcription; thus this protein may function in transcription regulation. Multiple transcript variants have been found for this gene. [provided by RefSeq, Apr 2016]
The protein encoded by this gene is a Kruppel-related zinc finger protein which is characterized by the presence of an N-terminal repressor domain, the Kruppel-associated box (KRAB). The KRAB domain is a potent repressor of transcription; thus this protein may function in transcription regulation. Multiple transcript variants have been found for this gene. [provided by RefSeq, Apr 2016]
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Prostatic Neoplasms | 472 | 0.0 | 0.0 |
| Stomach Neoplasms | 287 | 0.0 | 0.0 |
| Disease | Target Count | P-value |
|---|---|---|
| psoriasis | 6514 | 3.7e-10 |
| Pick disease | 1856 | 4.6e-07 |
| osteosarcoma | 7766 | 2.7e-05 |
| oligodendroglioma | 2768 | 9.4e-04 |
| group 4 medulloblastoma | 1806 | 1.2e-03 |
| intraductal papillary-mucinous adenoma (IPMA) | 2872 | 1.5e-03 |
| pancreatic ductal adenocarcinoma liver metastasis | 1911 | 2.6e-03 |
| astrocytic glioma | 2530 | 4.1e-03 |
| Multiple myeloma | 1296 | 5.0e-03 |
| ovarian cancer | 8297 | 9.1e-03 |
| adrenocortical carcinoma | 1385 | 1.1e-02 |
| ependymoma | 4559 | 2.1e-02 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2902 | 3.5e-02 |
| Disease | log2 FC | p |
|---|---|---|
| adrenocortical carcinoma | 1.176 | 1.1e-02 |
| astrocytic glioma | 2.100 | 4.1e-03 |
| ependymoma | 1.400 | 2.1e-02 |
| group 4 medulloblastoma | 1.100 | 1.2e-03 |
| intraductal papillary-mucinous adenoma (... | 1.500 | 1.5e-03 |
| intraductal papillary-mucinous carcinoma... | 1.100 | 3.5e-02 |
| Multiple myeloma | -2.044 | 5.0e-03 |
| oligodendroglioma | 2.200 | 9.4e-04 |
| osteosarcoma | 1.876 | 2.7e-05 |
| ovarian cancer | -1.200 | 9.1e-03 |
| pancreatic ductal adenocarcinoma liver m... | 2.748 | 2.6e-03 |
| Pick disease | 1.500 | 4.6e-07 |
| psoriasis | -1.400 | 3.7e-10 |
MALTQVRLTFRDVAIEFSQEEWKCLDPAQRILYRDVMLENYWNLVSLGLCHFDMNIISMLEEGKEPWTVK 1 - 70 SCVKIARKPRTPECVKGVVTDIPPKCTIKDLLPKEKSSTEAVFHTVVLERHESPDIEDFSFKEPQKNVHD 71 - 140 FECQWRDDTGNYKGVLMAQKEGKRDQRDRRDIENKLMNNQLGVSFHSHLPELQLFQGEGKMYECNQVEKS 141 - 210 TNNGSSVSPLQQIPSSVQTHRSKKYHELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHS 211 - 280 GEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAF 281 - 350 RGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHT 351 - 420 GEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVF 421 - 490 TQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHS 491 - 560 GEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVF 561 - 630 RHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHT 631 - 700 GEKPYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAF 701 - 770 RVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASHHRMHTGEKPYK 771 - 818 //
