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Tbio
ZMYM3
Zinc finger MYM-type protein 3

Protein Summary
Description
Plays a role in the regulation of cell morphology and cytoskeletal organization. This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000314425
  • ENSP00000322845
  • ENSG00000147130
  • ENST00000373981
  • ENSP00000363093
  • ENST00000373998
  • ENSP00000363110

Symbol
  • DXS6673E
  • KIAA0385
  • ZNF261
  • MYM
  • XFIM
  • ZNF261
  • DXS6673E
  • ZNF198L2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
ligand (protein) perturbation
0.83
transcription factor perturbation
0.74
microRNA
0.65
virus perturbation
0.64
disease perturbation
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.11   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 137   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.11   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 137   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0