ZACN
Zinc-activated ligand-gated ion channel
Protein Summary
Zinc-activated ligand-gated ion channel. LGICZ1 is a zinc-activated ligand-gated ion channel that defines a new subgroup of the cysteine-loop superfamily of ligand-gated ion channels (Davies et al., 2003 [PubMed 12381728]).[supplied by OMIM, Mar 2008]
- ENST00000334586
- ENSP00000334854
- ENSG00000186919
- ENST00000421794
- ENSP00000391936
- ENST00000425015
- ENSP00000397489
- L2
- LGICZ
- LGICZ1
- ZAC
- L2
- ZAC
- ZAC1
- LGICZ
- LGICZ1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
cell line | 0.73 | ||
protein domain | 0.73 | ||
molecular function | 0.7 | ||
tissue | 0.53 | ||
cellular component | 0.44 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 6.46 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 76 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 6.46 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 76 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 10
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 3
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 1