Tbio XKR3 XK-related protein 3

Protein Summary

Description

XKRX (MIM 300684) and XKR3 are homologs of the Kell blood group precursor XK (MIM 314850), which is a putative membrane transporter and a component of the XK/Kell complex of the Kell blood group system (Calenda et al., 2006 [PubMed 16431037]).[supplied by OMIM, Mar 2008]

Uniprot Accession IDs

• Q5GH77
• B2RPN1
• Q52PG8
• Q8N7E1

Gene Name

• XKR3

Ensembl ID

• ENST00000331428
• ENSP00000331704
• ENSG00000172967

Symbol

• XRG3
• XRG3
• XTES

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell line	0.62
tissue sample	0.37
biological term	0.33
phenotype	0.32
tissue	0.31

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.42   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 69   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.42   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 69   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0