| Tdark | Putative Wilms tumor upstream neighbor 1 gene protein |
This gene is located upstream of the Wilms tumor 1 (WT1) gene; these two genes are bi-directionally transcribed from the same promoter region. This gene is imprinted in kidney, with preferential expression from the paternal allele. Imprinting defects at chromosome 11p13 may contribute to tumorigenesis. [provided by RefSeq, May 2014]
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Nephroblastoma | 51 | 4.758 | 2.4 |
| Wilson-Turner syndrome | 14 | 3.595 | 1.8 |
| Ovarian clear cell adenocarcinoma | 1 | 3.251 | 1.6 |
