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Tbio
WBP2NL
Postacrosomal sheath WW domain-binding protein

Protein Summary
Description
May play a role in meotic resumption and pronuclear formation, mediated by a WW domain-signaling pathway during fertilization. WBP2NL is a sperm-specific WW domain-binding protein that promotes meiotic resumption and pronuclear development during oocyte fertilization (Wu et al., 2007 [PubMed 17289678]).[supplied by OMIM, Mar 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000328823
  • ENSP00000332983
  • ENSG00000183066
  • ENST00000329620
  • ENSP00000328800
  • ENST00000436265
  • ENSP00000401002

Symbol
  • PAWP
  • PAWP
  • GRAMD7
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.65
histone modification site profile
0.64
gene perturbation
0.56
tissue sample
0.56
virus perturbation
0.5


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.52   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 91   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.52   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0