| Tbio | Vacuolar protein sorting-associated protein 28 homolog |
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.
This gene encodes a protein subunit of the ESCRT-I complex (endosomal complexes required for transport), which functions in the transport and sorting of proteins into subcellular vesicles. This complex can also be hijacked to facilitate the budding of enveloped viruses from the cell membrane. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
This gene encodes a protein subunit of the ESCRT-I complex (endosomal complexes required for transport), which functions in the transport and sorting of proteins into subcellular vesicles. This complex can also be hijacked to facilitate the budding of enveloped viruses from the cell membrane. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| ovarian cancer | 8520 | 2.9e-07 |
| osteosarcoma | 7950 | 1.3e-06 |
| Multiple myeloma | 1332 | 1.1e-03 |
| diabetes mellitus | 1728 | 1.2e-03 |
| Disease | log2 FC | p |
|---|---|---|
| diabetes mellitus | -1.200 | 1.2e-03 |
| Multiple myeloma | 1.196 | 1.1e-03 |
| osteosarcoma | -1.715 | 1.3e-06 |
| ovarian cancer | 2.600 | 2.9e-07 |
