Tbio VN1R1 Vomeronasal type-1 receptor 1

Protein Summary

Description

Putative pheromone receptor. Pheromones are chemical signals that elicit specific behavioral responses and physiologic alterations in recipients of the same species. The protein encoded by this gene is similar to pheromone receptors and is primarily localized to the olfactory mucosa. An alternate splice variant of this gene is thought to exist, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q9GZP7
• B3KSV5
• Q7Z5H8
• Q7Z5H9

Gene Name

• VN1R1

Ensembl ID

• ENST00000321039
• ENSP00000322339
• ENSG00000178201

Symbol

• V1RL1
• VNR19I1
• V1RL1
• ZVNH1
• ZVNR1
• VNR19I1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.69
tissue	0.56
small molecule perturbation	0.54
cell line	0.52
cell type or tissue	0.42

Protein Classes

DTO Classes

Protein / G-protein Coupled Receptor / Class A Rhodopsin Like / Vomeronasal Receptor / Vomeronasal Type-1 Receptor 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 56.15   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 166   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 56.15   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 166   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0