Tbio UTP23 rRNA-processing protein UTP23 homolog

Protein Summary

Description

Involved in rRNA-processing and ribosome biogenesis.

Uniprot Accession IDs

• Q9BRU9
• B2RE25
• Q96NJ8

Gene Name

• UTP23

Ensembl ID

• ENST00000309822
• ENSP00000308332
• ENSG00000147679

Symbol

• C8orf53
• C8orf53

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.91
transcription factor binding site profile	0.77
cell type or tissue	0.71
hub protein	0.71
histone modification site profile	0.7

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.76   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 70   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.76   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0