Property Summary

NCBI Gene PubMed Count 157
PubMed Score 92.33
PubTator Score 97.64

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (3)

Disease log2 FC p
astrocytic glioma -1.200 3.3e-02
lung cancer -4.100 3.8e-02
ovarian cancer -2.400 6.9e-03

Protein-protein Interaction (2)

Gene RIF (35)

PMID Text
25204743 Data suggest that both human ubiquitin and HFBII (hydrophobin-II from Trichoderma reesei) exhibit a critical surface hydration level (or effective hydrophobic interface at the surface) at which percolation transition of water network occurs.
24367661 UbB was significantly increased in prolonged Trichostatin A-selected HeLa cells and it played a key role in the maintenance of cervical cancer stem-like cells
24318982 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
24022007 downregulation of ubiquitin through Ubb-KD is a potential anti-cancer treatment by inhibiting ubiquitination at multiple sites related to oncogenic pathways and by weakening the ability of cancer cells to overcome increased stress.
22797007 A significant decrease in amyloid beta deposition and plaque formation suggests a role for the ubiquitin-proteasome system in the amyloid pathology of Alzheimer's disease.
22082077 age-dependent accumulation of Ubb(+1) , and how Ubb(+1) -mediated proteasome inhibition may contribute to Alzheimer's disease. [review]
21544573 Studies indicate that biomedical research on ubiquitin moves into translational research and drug discovery.
21480003 Studies indicate that DUBs recycle ubiquitin by processing polyubiquitin chains to generate free ubiquitin, and can be regulated by ubiquitination or phosphorylation.
21378163 analysis of orexin receptor 1 and 2 -arrestin-ubiquitin complexes
21059367 The results of this study demonstrated that the UBB mutation caused the subtle defect in spatial reference memory formation, caused by a decrease in forebrain proteasome activity.
20826778 Results suggest that the interaction between E2-25K and UBB(+1) is critical for the synthesis and accumulation of UBB(+1)-anchored polyubiquitin, which results in proteasomal inhibition and neuronal cell death.
20491623 Studies indicate that indicating that the inhibition of the ubiquitin-proteasome system could be used as a novel approach for cancer therapy.
19516896 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
19214209 The expression a mutant human UBB analogous (UB14) in yeast markedly enhanced cellular susceptibility to toxic protein aggregates.
18596088 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
17931355 analyse the expression of mutant ubiquitin (UBB+1), in muscle biopsies from patients suffering from myotilinopathy and desminopathy
17609272 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
17405812 UBB(+1), at low expression levels, is efficiently degraded by the proteasome, but at high levels, the proteasome failed to degrade UBB(+1), causing its accumulation.
17395554 K63-polyubiquitination guards against chemical carcinogenesis by preventing mutagenesis and thus contributing to genomic stability
17237936 UBB+1, a mutant form of ubiquitin was present in the majority of NFTs, whereas co-existence of alpha-synuclein and UBB+1 was found in only a few neurons in cases of combined multiple system atrophy and Alzheimer's disease.
17067581 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
16808324 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
16775314 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
15994808 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
15452314 In sporadic inclusion-body myositis, UBB+1 may be pathogenic by inhibiting proteasome, thereby promoting accumulation of cytotoxic misfolded amyloid-beta and phosphorylated-tau.
12893422 The temporal localization of frame-shift ubiquitin-B and amyloid precursor protein, and complement proteins in the brain of non-demented control patients with increasing Alzheimer's disease pathology.
12883554 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
12871580 expression of UBB+1 causes proteasome inhibition and induces expression of heat-shock proteins; although UBB+1-expressing cells have a compromised ubiquitin-proteasome system, they are protected against oxidative stress
12610113 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
12055595 Molecular misreading of the ubiquitin B gene and hepatic mallory body formation.
11991975 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
11112487 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
11087860 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
11087859 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex
9525617 A di-Ub(K48)-hHR23A-Vpr ternary complex is formed with Lys-48-linked di-ubiquitin binding to the UBA1 domain in the Vpr-hHR23A complex

AA Sequence

MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLV      1 - 70
LRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKE     71 - 140
STLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD    141 - 210
YNIQKESTLHLVLRLRGGC                                                       211 - 229
//

Text Mined References (163)

PMID Year Title
25527291 2015 Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis.
25204743 2014 Protein-spanning water networks and implications for prediction of protein-protein interactions mediated through hydrophobic effects.
24784582 2014 Ubiquitin is phosphorylated by PINK1 to activate parkin.
24751536 2014 PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity.
24660806 2014 Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.
24367661 2013 Ubiquitin B in cervical cancer: critical for the maintenance of cancer stem-like cell characters.
24022007 2013 Downregulation of ubiquitin level via knockdown of polyubiquitin gene Ubb as potential cancer therapeutic intervention.
23533145 2013 In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
22797007 2012 Mutant ubiquitin decreases amyloid ? plaque formation in a transgenic mouse model of Alzheimer's disease.
22082077 2012 Review: unchained maladie - a reassessment of the role of Ubb(+1) -capped polyubiquitin chains in Alzheimer's disease.
21762696 2011 Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3).
21630459 2011 Proteomic characterization of the human sperm nucleus.
21544573 2011 A baker's dozen of ubiquitin.
21516116 2011 Next-generation sequencing to generate interactome datasets.
21480003 2011 PTMs in conversation: activity and function of deubiquitinating enzymes regulated via post-translational modifications.
21378163 2011 Temporal profiling of orexin receptor-arrestin-ubiquitin complexes reveals differences between receptor subtypes.
21059367 2011 Alzheimer-associated mutant ubiquitin impairs spatial reference memory.
20924359 2010 Ubiquitination and deubiquitination of NP protein regulates influenza A virus RNA replication.
20826778 2010 Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity.
20491623 2010 The ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention.
19754430 2009 The emerging complexity of protein ubiquitination.
19608861 2009 Lysine acetylation targets protein complexes and co-regulates major cellular functions.
19214209 2009 Disease-associated mutant ubiquitin causes proteasomal impairment and enhances the toxicity of protein aggregates.
18719106 2008 Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks.
18313049 2008 A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95.
18082604 2007 A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway.
18029035 2008 Involvement of Ymer in suppression of NF-kappaB activation by regulated interaction with lysine-63-linked polyubiquitin chain.
17936559 2007 The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
17931355 2008 Expression of mutant ubiquitin (UBB+1) and p62 in myotilinopathies and desminopathies.
17803915 2007 SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release.
17719543 2007 Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain.
17719541 2007 Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation.
17662948 2007 Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors.
17571083 2007 Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration.
17405812 2007 Dose-dependent inhibition of proteasome activity by a mutant ubiquitin associated with neurodegenerative disease.
17395554 2007 Formation of lysine 63-linked poly-ubiquitin chains protects human lung cells against benzo[a]pyrene-diol-epoxide-induced mutagenicity.
17323924 2007 Mass spectrometric characterization of the affinity-purified human 26S proteasome complex.
17310990 2007 Human INT6 interacts with MCM7 and regulates its stability during S phase of the cell cycle.
17237936 2007 Mutant ubiquitin and p62 immunoreactivity in cases of combined multiple system atrophy and Alzheimer's disease.
17203973 2007 The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells.
17081983 2006 Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
17047224 2006 Regulation and function of IKK and IKK-related kinases.
16997282 2006 NF-kappaB functions in the nervous system: from development to disease.
16931761 2006 ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage.
16701206 2006 Cell survival through Trk neurotrophin receptors is differentially regulated by ubiquitination.
16651270 2006 Gli2 is targeted for ubiquitination and degradation by beta-TrCP ubiquitin ligase.
16630834 2006 Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons.
16625196 2006 DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
16581786 2006 The ETS protein MEF is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2.
16543144 2006 Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain.
16510124 2006 The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination.
16502470 2006 Human colostrum: identification of minor proteins in the aqueous phase by proteomics.
16499958 2006 Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin.
16443603 2006 Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation.
16429130 2006 Regulation of ubiquitin-binding proteins by monoubiquitination.
16407834 2006 Cbl escapes Cdc42-mediated inhibition by downregulation of the adaptor molecule betaPix.
16407252 2006 PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination.
16288044 2005 Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox.
16286470 2006 Cooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signaling.
16267042 2005 Site-specific monoubiquitination of IkappaB kinase IKKbeta regulates its phosphorylation and persistent activation.
16252010 2005 TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor.
16189514 2005 Towards a proteome-scale map of the human protein-protein interaction network.
16137618 2005 Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway.
16027724 2005 Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation.
16023596 2005 The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.
15886351 2005 Response of the ubiquitin-proteasome pathway to changes in muscle activity.
15781449 2005 Ubiquitination of APOBEC3G by an HIV-1 Vif-Cullin5-Elongin B-Elongin C complex is essential for Vif function.
15761153 2005 High-throughput mapping of a dynamic signaling network in mammalian cells.
15721744 2005 p75NTR--live or let die.
15694335 2005 The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15469984 2004 Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1.
15469821 2004 An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant.
15466860 2004 Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis.
15452314 2004 Mutant ubiquitin UBB+1 is accumulated in sporadic inclusion-body myositis muscle fibers.
15342556 2004 Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.
15308666 2004 Interaction of TRAF6 with MAST205 regulates NF-kappaB activation and MAST205 stability.
15276183 2004 MD-2: the Toll 'gatekeeper' in endotoxin signalling.
15231748 2004 Functional proteomics mapping of a human signaling pathway.
15149598 2004 Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage.
15143060 2004 The trihelical bundle subdomain of the GGA proteins interacts with multiple partners through overlapping but distinct sites.
15125833 2004 The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes.
15120077 2004 The Ubx2 and Ubx3 cofactors direct Cdc48 activity to proteolytic and nonproteolytic ubiquitin-dependent processes.
15105460 2004 S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function.
15057824 2004 The DNA sequence and biology of human chromosome 19.
15039775 2004 Interactions of GGA3 with the ubiquitin sorting machinery.
15029244 2004 Mammalian Cdh1/Fzr mediates its own degradation.
14764729 2004 Microtubule-associated serine/threonine kinase-205 kDa and Fc gamma receptor control IL-12 p40 synthesis and NF-kappa B activation.
14755250 2004 An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein.
14745543 2003 Lineage-specific homogenization of the polyubiquitin gene among human and great apes.
14743216 2004 A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.
14722266 2004 Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins.
14695475 2004 Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO.
14612456 2004 CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival.
14597671 2003 Disease-specific accumulation of mutant ubiquitin as a marker for proteasomal dysfunction in the brain.
14528304 2003 Enhancement of CIITA transcriptional function by ubiquitin.
12960054 2003 Regulation of follitropin receptor cell surface residency by the ubiquitin-proteasome pathway.
12893422 2003 The temporal localization of frame-shift ubiquitin-B and amyloid precursor protein, and complement proteins in the brain of non-demented control patients with increasing Alzheimer's disease pathology.
12883554 2003 A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter.
12871580 2003 Alzheimer's associated variant ubiquitin causes inhibition of the 26S proteasome and chaperone expression.
12857950 2003 Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates.
12853446 2003 Caspase-activated PAK-2 is regulated by subcellular targeting and proteasomal degradation.
12820959 2003 Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase.
12791267 2003 Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase.
12787561 Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).
12610113 2003 Retroviruses have differing requirements for proteasome function in the budding process.
12609980 2003 Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR .
12593796 2003 hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl.
12507430 2002 Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12367500 2002 New roles for ubiquitin in the assembly and function of neuronal circuits.
12239347 2002 Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu.
12234927 2002 Dual mode of degradation of Cdc25 A phosphatase.
12218189 2002 Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors.
12070128 2002 Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1.
12016299 2002 Emerging roles of ubiquitin in transcription regulation.
11991975 2002 Late assembly domain function can exhibit context dependence and involves ubiquitin residues implicated in endocytosis.
11931757 2002 Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication.
11790298 2002 Directed proteomic analysis of the human nucleolus.
11742988 2001 APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box.
11597332 2001 Ubiquitin junction, what's your function?
11320250 2001 Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity.
11285280 2001 Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint.
11231585 2001 The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27.
11173499 2001 Structure of a new crystal form of tetraubiquitin.
11146632 2001 The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins.
11112487 2000 Ubiquitination of HIV-1 and MuLV Gag.
11087860 2000 A role for ubiquitin ligase recruitment in retrovirus release.
11087859 2000 Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2.
11046148 2000 Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases.
11031247 2000 Secretory protein trafficking and organelle dynamics in living cells.
10995389 2000 Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1.
10882101 2000 TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway.
10871850 2000 Degradation of B-Myb by ubiquitin-mediated proteolysis: involvement of the Cdc34-SCF(p45Skp2) pathway.
10827953 2000 Rapid destruction of human Cdc25A in response to DNA damage.
10066798 1999 pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-src) signaling in breast cancer cells.
9660940 1998 A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif.
9644242 1998 Cloning of human polyubiquitin cDNAs and a ubiquitin-binding assay involving its in vitro translation product.
9525617 1998 Ubiquitin is covalently attached to the p6Gag proteins of human immunodeficiency virus type 1 and simian immunodeficiency virus and to the p12Gag protein of Moloney murine leukemia virus.
9504932 1998 Higher frequency of concerted evolutionary events in rodents than in man at the polyubiquitin gene VNTR locus.
9422699 1998 Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients.
8917096 1996 Heterogeneous structure of the polyubiquitin gene UbC of HeLa S3 cells.
8889548 1996 Normalization and subtraction: two approaches to facilitate gene discovery.
8702753 1996 p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins.
8275493 1994 Differential expression of heat shock proteins in pancreatic carcinoma.
8166633 1994 Synthetic, structural and biological studies of the ubiquitin system: the total chemical synthesis of ubiquitin.
8107144 1994 Structure of tetraubiquitin shows how multiubiquitin chains can be formed.
8087846 1994 Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain.
6275256 1981 Ubiquitin - protein conjugates.
6261785 1981 Protein A24 lyase activity in nucleoli of thioacetamide-treated rat liver releases histone 2A and ubiquitin from conjugated protein A24.
6092831 1984 Ubiquitination of proteins.
3041007 1987 Structure of ubiquitin refined at 1.8 A resolution.
3029682 1987 The human ubiquitin gene family: structure of a gene and pseudogenes from the Ub B subfamily.
2988935 1985 The human ubiquitin multigene family: some genes contain multiple directly repeated ubiquitin coding sequences.
2820408 1987 Cloning and sequence analysis of a cDNA encoding poly-ubiquitin in human ovarian granulosa cells.
2581967 1985 Nucleotide sequence analysis of a cDNA encoding human ubiquitin reveals that ubiquitin is synthesized as a precursor.
2537950 1989 Ubiquitin mRNA is a major stress-induced transcript in mammalian cells.
2154095 1990 Localization of the human UbB polyubiquitin gene to chromosome band 17p11.1-17p12.
1850507 1991 The human ubiquitin-52 amino acid fusion protein gene shares several structural features with mammalian ribosomal protein genes.
1657614 1991 Effect of ubiquitin on platelet functions: possible identity with platelet activity suppressive lymphokine (PASL).
1370760 1992 Differential expression of translation-associated genes in benign and malignant human breast tumours.
1128706 1975 Molecular conservation of 74 amino acid sequence of ubiquitin between cattle and man.
124018 1975 Hybrid troponin reconstituted from vertebrate and arthropod subunits.