Property Summary

NCBI Gene PubMed Count 53
PubMed Score 124.21
PubTator Score 28.29

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (2)

Expression

  Differential Expression (2)

Disease log2 FC p
Multiple myeloma 1.197 0.004
lung cancer -2.300 0.044

Gene

PDB

5HPK   4UG0   4V6X   5AJ0   4P4H   5JBY   5HPS   5HPT   2LJ5   2MBH   2MJB   2MUR   2N3U   2N3V   2N3W   2NBD   2NBE   2RSU   4HJK   4JIO   4PIG   4PIH   4PIJ   4RF0   4RF1   4S1Z   4XKL   5HPL   5J8P   5JBV  

  Ortholog (14)

Gene RIF (3)

PMID Text
25631074 Cellular biotinylated ubiquitin A-52 residue ribosomal protein fusion product 1 protein (UBA52, ubiquitin-60S ribosomal protein L40) is incorporated into HIV-1 Gag virus-like particles
24139988 Select activation-degradation regions like the ones found in EKLF and SREBP1a function in part through their ability to form noncovalent interactions with ubiquitin.
23874603 Cellular biotinylated ubiquitin A-52 residue ribosomal protein fusion product 1 protein (UBA52, ubiquitin-60S ribosomal protein L40) is incorporated into HIV-1 Gag virus-like particles

AA Sequence

MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLV      1 - 70
LRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK                 71 - 128
//

Text Mined References (68)

PMID Year Title
25527291 2015 Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis.
24784582 2014 Ubiquitin is phosphorylated by PINK1 to activate parkin.
24751536 2014 PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity.
24660806 2014 Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.
24139988 2013 Structural characterization of a noncovalent complex between ubiquitin and the transactivation domain of the erythroid-specific factor EKLF.
23636399 2013 Structures of the human and Drosophila 80S ribosome.
23533145 2013 In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
23169626 2013 A ribosome-specialized translation initiation pathway is required for cap-dependent translation of vesicular stomatitis virus mRNAs.
22729708 2012 Determination of structural fluctuations of proteins from structure-based calculations of residual dipolar couplings.
22020285 2011 Image-based genome-wide siRNA screen identifies selective autophagy factors.
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