Tbio TUSC1 Tumor suppressor candidate gene 1 protein

Protein Summary

Description

This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q2TAM9
• A0PJ78
• Q67GI3
• Q86SS1
• Q8TAH8

Gene Name

• TUSC1

Ensembl ID

• ENST00000358022
• ENSP00000350716
• ENSG00000198680

Symbol

• TSG9
• TSG-9
• CCDC89B

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
ligand (protein) perturbation	0.83
tissue sample	0.63
virus perturbation	0.59
tissue	0.57
cellular component	0.52

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.94   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 111   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.94   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 111   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0