Tdark TTC22 Tetratricopeptide repeat protein 22

Protein Summary

Description

This gene encodes a protein with seven tetratricopeptide (TPR) repeats. Tetratricopeptide repeat containing motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2011]

Uniprot Accession IDs

• Q5TAA0
• Q9NWT4
• TPR repeat protein 22

Gene Name

• TTC22

Ensembl ID

• ENST00000371274
• ENSP00000360321
• ENSG00000006555
• ENST00000371276
• ENSP00000360323

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cellular component	0.75
virus perturbation	0.59
cell type or tissue	0.57
microRNA	0.55
tissue sample	0.5

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.83   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 21   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.83   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 21   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0