TSSK6
Testis-specific serine/threonine-protein kinase 6
Protein Summary
Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling (By similarity). This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm. [provided by RefSeq, Jan 2012]
- ENST00000585580
- ENSP00000466477
- ENSG00000178093
- ENST00000587522
- ENSP00000466056
- SSTK
- CT72
- SSTK
- TSSK4
- FKSG82
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
molecular function | 0.95 | ||
transcription factor binding site profile | 0.89 | ||
gene perturbation | 0.76 | ||
histone modification site profile | 0.74 | ||
cell type or tissue | 0.73 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 119.9 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 154 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 119.9 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 154 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 9
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0