Tchem TSSK3 Testis-specific serine/threonine-protein kinase 3

Protein Summary

Description

May be involved in a signaling pathway during male germ cell development or mature sperm function. This gene encodes a kinase expressed exclusively in the testis that is thought to play a role in either germ cell differentiation or mature sperm function. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q96PN8
• Q5TEE5
• TSK-3

Gene Name

• TSSK3

Ensembl ID

• ENST00000373534
• ENSP00000362634
• ENSG00000162526

Symbol

• SPOGA3
• STK22C
• TSK3
• SPOGA3
• STK22C
• STK22D

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.95
tissue sample	0.72
protein domain	0.58
cell type or tissue	0.53
histone modification site profile	0.53

Protein Classes

PANTHER Classes

Protein / Transferase / Kinase / Protein Kinase / Non-receptor Serine/threonine Protein Kinase / Testis-specific Serine/threonine-protein Kinase 3

DTO Classes

Protein / Kinase / Protein Kinase / Camk Group / Tssk Family / Testis-specific Serine/threonine-protein Kinase 3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.57   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 73   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.57   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 73   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0