| Tbio | E3 ubiquitin-protein ligase TRIM62 |
E3 ubiquitin ligase whose activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| ovarian cancer | 8520 | 1.4e-09 |
| ependymoma | 4679 | 2.3e-09 |
| atypical teratoid/rhabdoid tumor | 357 | 3.4e-07 |
| psoriasis | 6694 | 7.6e-04 |
| osteosarcoma | 7950 | 3.2e-03 |
| Disease | log2 FC | p |
|---|---|---|
| atypical teratoid/rhabdoid tumor | -1.300 | 3.4e-07 |
| ependymoma | -1.100 | 2.3e-09 |
| osteosarcoma | -1.307 | 3.2e-03 |
| ovarian cancer | 1.100 | 1.4e-09 |
| psoriasis | 1.400 | 7.6e-04 |
| Species | Source | Disease |
|---|---|---|
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA | ||
| Inparanoid OMA | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA |
MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLKLAN 1 - 70 IVERYSSFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFDELQRELK 71 - 140 DQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTD 141 - 210 IEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQY 211 - 280 TIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGV 281 - 350 HYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFL 351 - 420 DYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI 421 - 475 //
