Tbio TRAPPC4 Trafficking protein particle complex subunit 4

Protein Summary

Description

May play a role in vesicular transport from endoplasmic reticulum to Golgi.

Uniprot Accession IDs

• Q9Y296
• A8K3A5
• B4DME1

Gene Name

• TRAPPC4

Ensembl ID

• ENST00000434101
• ENSP00000405033
• ENSG00000196655
• ENST00000533632
• ENSP00000436005
• ENST00000629243
• ENSP00000487467
• ENSG00000280495
• ENST00000629713
• ENSP00000486496

Symbol

• SBDN
• SBDN
• TRS23
• PTD009
• CGI-104
• HSPC172
• SYNBINDIN

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.95
histone modification site profile	0.88
disease perturbation	0.87
interacting protein	0.86
transcription factor binding site profile	0.77

Protein Classes

PANTHER Classes

Protein / Membrane Traffic Protein / Trafficking Protein Particle Complex Subunit 4

DTO Classes

Protein / Transporter / Trafficking Protein Particle Complex Subunit 4

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.9   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 258   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.9   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 258   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0