Tbio TRAPPC11 Trafficking protein particle complex subunit 11

Protein Summary

Description

Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage. The protein encoded by this gene is a subunit of the TRAPP (transport protein particle) tethering complex, which functions in intracellular vesicle trafficking. This subunit is involved in early stage endoplasmic reticulum-to-Golgi vesicle transport. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Uniprot Accession IDs

• Q7Z392
• A4QPB8
• B2RCD6
• Q5U5I7
• Q6FI73
• Q86T25
• Q9H0L1
• Q9H5K9
• Q9H8Q1
• Q9H9I7

Gene Name

• TRAPPC11

Ensembl ID

• ENST00000334690
• ENSP00000335371
• ENSG00000168538
• ENST00000357207
• ENSP00000349738

Symbol

• C4orf41
• GRY
• FOIGR
• LGMD2S
• C4orf41
• LGMDR18

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.92
kinase perturbation	0.84
cell type or tissue	0.61
tissue sample	0.6
cell line	0.57

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.01   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 38   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.01   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 38   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0