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Tdark Transmembrane protein 51


 Comments

Property Summary

NCBI Gene PubMed Count 8
PubMed Score 0.55
PubTator Score 0.24

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count P-value
tuberculosis 1563 1.7e-05
invasive ductal carcinoma 2950 1.8e-04
interstitial cystitis 2299 2.6e-04
cystic fibrosis 1670 2.8e-04
group 4 medulloblastoma 1875 4.6e-03
Disease Target Count Z-score Confidence
Scoliosis 40 3.03 1.5

Expression

  Differential Expression (5)

Disease log2 FC p
cystic fibrosis 1.241 2.8e-04
tuberculosis -1.600 1.7e-05
interstitial cystitis -1.100 2.6e-04
group 4 medulloblastoma -1.100 4.6e-03
invasive ductal carcinoma 1.200 1.8e-04

Synonym

Accession Q9NW97 A8K819
Symbols C1orf72

Gene

TMEM51

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

 UniProt Keyword (7)

 GO Component (1)

 Compartment GO Term (7)

 HCA RNA Cell Line (55)

See all...

Pathway (1)

Protein-protein Interaction (16)

SLC39A11   HSPA12A   WWP2   NEDD4   ITCH   NEDD4L   WWP1   TTI1   PTER   C20orf24   FNDC3A   GALC   FAM114A2   PDCD4   CUEDC1   HECW2  

Gene RIF (1)

PMID Text
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

AA Sequence 

MMAQSKANGSHYALTAIGLGMLVLGVIMAMWNLVPGFSAAEKPTAQGSNKTEVGGGILKSKTFSVAYVLV      1 - 70
GAGVMLLLLSICLSIRDKRKQRQGEDLAHVQHPTGAGPHAQEEDSQEEEEEDEEAASRYYVPSYEEVMNT     71 - 140
NYSEARGEEQNPRLSISLPSYESLTGLDETTPTSTRADVEASPGNPPDRQNSKLAKRLKPLKVRRIKSEK    141 - 210
LHLKDFRINLPDKNVPPPSIEPLTPPPQYDEVQEKAPDTRPPD                               211 - 253
//

Text Mined References (11)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
21406692 2011 System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
16710414 2006 The DNA sequence and biological annotation of human chromosome 1.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15342556 2004 Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
8889548 1996 Normalization and subtraction: two approaches to facilitate gene discovery.