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Tdark Transmembrane protein 132C


 Comments

Property Summary

NCBI Gene PubMed Count 4
PubMed Score 0.33
PubTator Score 0.33

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count Z-score Confidence
Bipolar Disorder 266 0.0 1.0

Expression

  Differential Expression (16)

Disease log2 FC p
osteosarcoma -4.809 1.7e-06
glioblastoma -1.700 1.9e-03
Atopic dermatitis -1.100 5.9e-04
intraductal papillary-mucinous adenoma (... -1.200 1.9e-03
intraductal papillary-mucinous carcinoma... -1.100 2.9e-03
intraductal papillary-mucinous neoplasm ... -1.400 7.1e-03
breast carcinoma -1.400 5.7e-04
fibroadenoma -1.800 4.4e-03
interstitial cystitis -1.400 2.4e-05
pediatric high grade glioma -1.200 6.7e-03
group 4 medulloblastoma -1.500 1.3e-04
pilocytic astrocytoma 1.800 1.0e-06
subependymal giant cell astrocytoma -1.252 2.8e-02
ductal carcinoma in situ -3.100 4.2e-05
invasive ductal carcinoma -3.400 2.3e-04
psoriasis -2.000 2.3e-88

Synonym

Accession Q8N3T6 Q69YX8
Symbols PPP1R152

Gene

TMEM132C

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

 UniProt Keyword (8)

 GO Component (1)

 Compartment GO Term (7)

 GWAS Trait (3)

 HCA RNA Cell Line (23)

See all...

Pathway (1)

Gene RIF (2)

PMID Text
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
18187620 Knockdown of transmembrane protein 132C (TMEM132C) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells

AA Sequence 

MRSEGAAPGPAAPLCGALSLLLGALLGKVIEGHGVTDNIQRFSSLPPYLPVSYHILRAETSFFLKEANQD      1 - 70
LLRNSSLQARVESFFTYKTRQPPVLNASYGPFSVEKVVPLDLMLTSNFLGPTNKFSFDWKLKAHILRDKV     71 - 140
YLSRPKVQVLFHIMGRDWDDHGAGEKLPCLRVFAFRETREVRGSCRLKGDLGLCVAELELLSSWFSAPTV    141 - 210
GAGRKKSMDQPEGTPVELYYTVHPGNERGDCAGGDFRKGNAIRPGKDGLEETTSHLQRIGTVGLYRAQDS    211 - 280
AQLSELRLDGNVVIWLPSRPVKQGEVVTAYVTISSNSSVDLFILRAKVKKGVNILSAQTREPRQWGVKQE    281 - 350
VGSGGKHVTATVACQRLGPSPRNRSSSLFNEVVQMNFEIASFSSLSGTQPITWQVEYPRKGTTDIAVSEI    351 - 420
FVSQKDLVGIVPLAMDTEILNTAVLTGKTVAMPIKVVSVEENSAVMDISESVECKSTDEDVIKVSERCDY    421 - 490
IFVNGKEIKGKMDAVVNFTYQYLSAPLCVTVWVPRLPLQIEVSDTELSQIKGWRVPIVTNKRPTRESEDE    491 - 560
DEEERRGRGCALQYQHATVRVLTQFVSEGAGPWGQPNYLLSPNWQFDITHLVADFMKLEEPHVATLQDSR    561 - 630
VLVGREVGMTTIQVLSPLSDSILAEKTITVLDDKVSVTDLAIQLVAGLSVALYPNAENSKAVTAVVTAEE    631 - 700
VLRTPKQEAVFSTWLQFSDGSVTPLDIYDTKDFSLAATSQDEAVVSVPQPRSPRWPVVVAEGEGQGPLIR    701 - 770
VDMTIAEACQKSKRKSILAVGVGNVRVKFGQNDADSSPGGDYEEDEIKNHASDRRQKGQHHERTGQDGHL    771 - 840
YGSSPVEREEGALRRATTTARSLLDNKVVKNSRADGGRLAGEGQLQNIPIDFTNFPAHVDLPKAGSGLEE    841 - 910
NDLVQTPRGLSDLEIGMYALLGVFCLAILVFLINCATFALKYRHKQVPLEGQASMTHSHDWVWLGNEAEL    911 - 980
LESMGDAPPPQDEHTTIIDRGPGACEESNHLLLNGGSHKHVQSQIHRSADSGGRQGREQKQDPLHSPTSK    981 - 1050
RKKVKFTTFTTIPPDDSCPTVNSIVSSNDEDIKWVCQDVAVGAPKELRNYLEKLKDKA               1051 - 1108
//

Text Mined References (6)

PMID Year Title
24025145 2013 A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.
23456168 2013 Genome-wide association study in Han Chinese identifies three novel loci for human height.
21423239 2012 A genome-wide association study of attempted suicide.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
17974005 2007 The full-ORF clone resource of the German cDNA Consortium.
16541075 2006 The finished DNA sequence of human chromosome 12.