| Tbio | Transmembrane emp24 domain-containing protein 4 |
Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis (By similarity).
Comments
| Disease | Target Count | P-value |
|---|---|---|
| lung carcinoma | 2843 | 1.6e-28 |
| osteosarcoma | 7950 | 5.2e-07 |
| ovarian cancer | 8520 | 9.0e-07 |
| atypical teratoid / rhabdoid tumor | 5112 | 9.5e-06 |
| ependymoma | 4679 | 1.2e-05 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 5.1e-05 |
| tuberculosis | 2010 | 8.3e-05 |
| adult high grade glioma | 3801 | 2.2e-04 |
| primitive neuroectodermal tumor | 3035 | 2.7e-04 |
| glioblastoma | 5792 | 2.7e-04 |
| intraductal papillary-mucinous adenoma (IPMA) | 2955 | 3.1e-04 |
| medulloblastoma, large-cell | 6241 | 4.6e-04 |
| adrenocortical carcinoma | 1428 | 9.6e-04 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 1.3e-03 |
| group 3 medulloblastoma | 4104 | 5.9e-03 |
| Disease | log2 FC | p |
|---|---|---|
| adrenocortical carcinoma | -1.150 | 9.6e-04 |
| adult high grade glioma | 1.600 | 2.2e-04 |
| atypical teratoid / rhabdoid tumor | 1.800 | 9.5e-06 |
| ependymoma | 1.100 | 1.2e-05 |
| glioblastoma | 1.700 | 2.7e-04 |
| group 3 medulloblastoma | 1.100 | 5.9e-03 |
| intraductal papillary-mucinous adenoma (... | -1.300 | 3.1e-04 |
| intraductal papillary-mucinous carcinoma... | -1.600 | 5.1e-05 |
| intraductal papillary-mucinous neoplasm ... | 1.100 | 1.3e-03 |
| lung carcinoma | 1.100 | 1.6e-28 |
| medulloblastoma, large-cell | 1.500 | 4.6e-04 |
| osteosarcoma | 2.206 | 5.2e-07 |
| ovarian cancer | -2.200 | 9.0e-07 |
| primitive neuroectodermal tumor | 1.100 | 2.7e-04 |
| tuberculosis | 1.100 | 8.3e-05 |
