| Tdark | Complex I assembly factor TIMMDC1, mitochondrial |
Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I.
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Mitochondrial complex I deficiency | 46 | 0.0 | 5.0 |
| Disease | Target Count | P-value |
|---|---|---|
| ovarian cancer | 8520 | 1.1e-03 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Juvenile rheumatoid arthritis | 111 | 3.215 | 1.6 |
| Celiac disease | 116 | 0.0 | 0.8 |
| Primary biliary cirrhosis | 51 | 0.0 | 3.0 |
| Species | Source | Disease |
|---|---|---|
| Inparanoid EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG |
MEVPPPAPRSFLCRALCLFPRVFAAEAVTADSEVLEERQKRLPYVPEPYYPESGWDRLRELFGKDEQQRI 1 - 70 SKDLANICKTAATAGIIGWVYGGIPAFIHAKQQYIEQSQAEIYHNRFDAVQSAHRAATRGFIRYGWRWGW 71 - 140 RTAVFVTIFNTVNTSLNVYRNKDALSHFVIAGAVTGSLFRINVGLRGLVAGGIIGALLGTPVGGLLMAFQ 141 - 210 KYSGETVQERKQKDRKALHELKLEEWKGRLQVTEHLPEKIESSLQEDEPENDAKKIEALLNLPRNPSVID 211 - 280 KQDKD 281 - 285 //
