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Tdark T-cell leukemia/lymphoma protein 1B

Enhances the phosphorylation and activation of AKT1 and AKT2.

 Comments

Property Summary

NCBI Gene PubMed Count 10
PubMed Score 16.34
PubTator Score 9.04

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (4)

Disease Target Count Z-score Confidence
Breast Neoplasms 445 0.0 0.0
Neoplasm Metastasis 168 0.0 0.0
Disease Target Count
Mammary Neoplasms 425
Disease Target Count Z-score Confidence
Cancer 2499 0.0 4.0
Disease Target Count Z-score Confidence
Strongyloidiasis 9 3.338 1.7
Leukemia 104 3.146 1.6

Expression

Synonym

Accession O95988 A6NEK7 Q6IAR7 Q9UBQ4
Symbols TML1
SYN-1

Gene

TCL1B

  Ortholog (4)

Species Source Disease
OMA EggNOG
OMA EggNOG
Inparanoid OMA
Inparanoid EggNOG

 UniProt Keyword (5)

 GO Function (2)

 GO Component (1)

 GO Process (2)

 Compartment GO Term (4)

 HCA RNA Cell Line (23)

See all...

Pathway (3)

Protein-protein Interaction (21)

ACAD11   MED13   HPS3   MED1   ARFGEF1   MED14   MAGI3   HPS5   MED4   MED29   MED22   MED24   MED10   NDE1   SAR1B   MED17   MED28   MED9   MED20   DISC1   MED8  

Gene RIF (2)

AA Sequence 

MASEASVRLGVPPGRLWIQRPGIYEDEEGRTWVTVVVRFNPSRREWARASQGSRYEPSITVHLWQMAVHT      1 - 70
RELLSSGQMPFSQLPAVWQLYPGRKYRAADSSFWEIADHGQIDSMEQLVLTYQPERKD                 71 - 128
//

Text Mined References (12)

PMID Year Title