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Tbio
TBPL2
TATA box-binding protein-like protein 2

Protein Summary
Description
Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000247219
  • ENSP00000247219
  • ENSG00000182521

Symbol
  • TBP2
  • TRF3
  • TBP2
  • TRF3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.58
biological process
0.53
cell type or tissue
0.5
tissue
0.47
cell line
0.44


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 94.67   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 116   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 94.67   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 116   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0