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Tbio
TBC1D14
TBC1 domain family member 14

Protein Summary
Description
Negative regulator of starvation-induced autophagosome formation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000409757
  • ENSP00000386921
  • ENSG00000132405
  • ENST00000448507
  • ENSP00000404041
  • ENST00000451522
  • ENSP00000388886

Symbol
  • KIAA1322
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.92
virus perturbation
0.85
transcription factor
0.81
disease perturbation
0.79
kinase perturbation
0.66


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.63   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 98   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.63   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 98   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0