Tdark SYNDIG1 Synapse differentiation-inducing gene protein 1

Protein Summary

Description

May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation. This gene encodes a protein that belongs to the interferon-induced transmembrane family of proteins. A similar protein in rat is thought to regulate the development of excitatory synapses. [provided by RefSeq, Jul 2013]

Uniprot Accession IDs

• Q9H7V2
• Q6IA30
• Q9H514
• SynDIG1

Gene Name

• SYNDIG1

Ensembl ID

• ENST00000376862
• ENSP00000366058
• ENSG00000101463

Symbol

• C20orf39
• TMEM90B
• DSPC2
• IFITMD5
• TMEM90B
• C20orf39

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.7
cellular component	0.69
tissue sample	0.65
tissue	0.58
cell line	0.55

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.81   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 12   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.81   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 12   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0