You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
SYCP1
Synaptonemal complex protein 1

Protein Summary
Description
Major component of the transverse filaments of synaptonemal complexes, formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000369518
  • ENSP00000358531
  • ENSG00000198765
  • ENST00000369522
  • ENSP00000358535
  • ENST00000618516
  • ENSP00000480997

Symbol
  • SCP1
  • CT8
  • SCP1
  • SCP-1
  • HOM-TES-14
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.78
cellular component
0.62
disease perturbation
0.62
trait
0.61
cell line
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 84.89   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 204   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 84.89   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 204   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 11
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0