Tbio STK31 Serine/threonine-protein kinase 31

Protein Summary

Description

This gene is similar to a mouse gene that encodes a putative protein kinase with a tudor domain, and shows testis-specific expression. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q9BXU1
• B4DZ06
• B7WPP5
• C9J4F9
• Q6PCD3
• Q9BXH8

Gene Name

• STK31

Ensembl ID

• ENST00000354639
• ENSP00000346660
• ENSG00000196335
• ENST00000355870
• ENSP00000348132
• ENST00000433467
• ENSP00000411852

Symbol

• SGK396
• TDRD8
• SGK396

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.9
gene perturbation	0.83
cell type or tissue	0.65
tissue sample	0.62
protein domain	0.58

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Transcription Cofactor / Serine/threonine-protein Kinase 31

Protein / Nucleic Acid Binding / Serine/threonine-protein Kinase 31

DTO Classes

Protein / Kinase / Protein Kinase / Other Group / Other-unique Family / Serine/threonine-protein Kinase 31

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.66   (req: < 5)

Gene RIFs: 11   (req: <= 3)

Antibodies: 219   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.66   (req: >= 5)

Gene RIFs: 11   (req: > 3)

Antibodies: 219   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0