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  7. Serine/threonine-protein kinase 31

Tchem Serine/threonine-protein kinase 31

This gene is similar to a mouse gene that encodes a putative protein kinase with a tudor domain, and shows testis-specific expression. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

 Comments

Property Summary

Ligand Count 1
NCBI Gene PubMed Count 11
PubMed Score 6.09
PubTator Score 7.17

Knowledge Summary

Patent (2,140)

TINX Plot

  Disease (2)

Expression

  Differential Expression (5)

Disease log2 FC p
intraductal papillary-mucinous adenoma (... 2.100 1.9e-05
intraductal papillary-mucinous carcinoma... 3.200 2.7e-03
intraductal papillary-mucinous neoplasm ... 2.600 4.2e-04
lung adenocarcinoma 1.100 7.1e-03
ovarian cancer -3.800 3.3e-10

Synonym

Accession Q9BXU1 B4DZ06 B7WPP5 C9J4F9 Q6PCD3 Q9BXH8
Symbols TDRD8
SGK396

Gene

STK31

PANTHER Protein Class (2)

  Ortholog (14)

Species Source Disease
OMA EggNOG
OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA
Inparanoid OMA EggNOG
OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA
OMA EggNOG
Inparanoid OMA EggNOG

 Collection (2)

 UniProt Keyword (10)

 GO Function (3)

 GO Component (3)

 GO Process (1)

 Compartment GO Term (11)

 MGI Phenotype (1)

 GWAS Trait (3)

 HCA RNA Cell Line (18)

See all...

Ligand (1)

Structure of compound 25 [PMID: 17935989]

compound 25 [PMID: 17935989]
pKi 5.85

Gene RIF (4)

AA Sequence 

MWVQGHSSRASATESVSFSGIVQMDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCP      1 - 70
QASSVLGNLDPNKIYGGLFSEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPLELQFSSVA     71 - 140
KKYKLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGTVIAQAEYGSVDIGEEVLKKGFAE    141 - 210
KCRLASRTDICEEKKLDPGQLVLRNLKSPIPLWGHRSNQSTFSRPKGHLSEKMTLDLKDENDAGNLITFP    211 - 280
KESLAVGDFNLGSNVSLEKIKQDQKLIEENEKLKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTN    281 - 350
HLEYTLKTYIDTRMKNLAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSL    351 - 420
AQENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEAVYGQAKEGAN    421 - 490
SDEILKKFYDWKCDKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEGSLISEDAMDNIDEILEKTES    491 - 560
SVCKELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIATVQAKYKDSIEFKKQLIEYLNKSPSVDHLL    561 - 630
SIKKTLKSLKALLRWKLVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIYHEREEYEMLTSLAQKWF    631 - 700
PELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKRPLVRSEVNGQIILLKGYSVDVDTEAKV    701 - 770
IERAATYHRAWREAEGDSGLLPLIFLFLCKSDPMAYLMVPYYPRANLNAVQANMPLNSEETLKVMKGVAQ    771 - 840
GLHTLHKADIIHGSLHQNNVFALNREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELKMGKPASPGSD    841 - 910
LYAYGCLLLWLSVQNQEFEINKDGIPKVDQFHLDDKVKSLLCSLICYRSSMTAEQVLNAECFLMPKEQSV    911 - 980
PNPEKDTEYTLYKKEEEIKTENLDKCMEKTRNGEANFDC                                   981 - 1019
//

Text Mined References (13)

PMID Year Title