Property Summary

NCBI Gene PubMed Count 18
PubMed Score 10.11
PubTator Score 18.18

Knowledge Summary


No data available


  Disease (2)

Disease Target Count
Peripheral Neuropathy 303
Disease Target Count Z-score Confidence
Synovial sarcoma 25 5.722 2.9
Parapsoriasis 6 3.081 1.5


Accession O60224 A8MYD4 B2RPE3 Q3SYD4 Q5JQZ0 Q9UJU9
Symbols CT5.4


PANTHER Protein Class (1)

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

Gene RIF (5)

24710929 The mRNA levels of SSX1 and SSX4 are associated with multiple myeloma clinical stage
24645645 SSX2, SSX3, and SSX4 are expressed only in 3.5% early-stage non-small cell lung cancer patients.
23625514 Our results suggest that GAGE, XAGE1 and SSX4 might each have a role in melanoma progression
21347689 we found that the SSX4 and MAGE-A3 genes are frequently expressed in brain tumor cell lines
15814740 existence of CD4+ T cells specific for multiple SSX-4 derived sequences in circulating lymphocytes from melanoma patients

AA Sequence


Text Mined References (18)

PMID Year Title
24710929 2014 Expression of cancer-testis antigen in multiple myeloma.
24645645 2014 SSX2-4 expression in early-stage non-small cell lung cancer.
23625514 2013 Effects of CT-Xp gene knock down in melanoma cell lines.
21347689 2011 Identification and functional characterization of glioma-specific promoters and their application in suicide gene therapy.
16189514 2005 Towards a proteome-scale map of the human protein-protein interaction network.
15814740 2005 CD4+ T cell responses to SSX-4 in melanoma patients.
15772651 2005 The DNA sequence of the human X chromosome.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12216073 2002 The SSX gene family: characterization of 9 complete genes.
12037676 2002 Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas.
12007189 2002 The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.
11433527 2001 Clinical impact of molecular and cytogenetic findings in synovial sarcoma.
11368913 2001 Cloning and characterization of spliced fusion transcript variants of synovial sarcoma: SYT/SSX4, SYT/SSX4v, and SYT/SSX2v. Possible regulatory role of the fusion gene product in wild type SYT expression.
11179834 2001 Expressions of cancer-testis antigens in human hepatocellular carcinomas.
11107170 2001 Molecular mechanisms underlying human synovial sarcoma development.
10359553 1999 A novel fusion gene, SYT-SSX4, in synovial sarcoma.
9378559 1997 SSX: a multigene family with several members transcribed in normal testis and human cancer.