| Tbio | Translocon-associated protein subunit beta |
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq, Jul 2008]
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq, Jul 2008]
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Prostatic Neoplasms | 495 | 0.0 | 0.0 |
| Disease | Target Count | P-value |
|---|---|---|
| ovarian cancer | 8520 | 1.3e-05 |
| group 3 medulloblastoma | 4104 | 4.4e-04 |
| lung cancer | 4740 | 6.2e-04 |
| glioblastoma | 5792 | 3.9e-03 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 6.5e-03 |
| diabetes mellitus | 1728 | 8.7e-03 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Calcaneonavicular coalition | 1 | 6.384 | 3.2 |
| Ectopic Cushing syndrome | 2 | 3.869 | 1.9 |
| Disease | log2 FC | p |
|---|---|---|
| diabetes mellitus | -1.200 | 8.7e-03 |
| glioblastoma | 1.100 | 3.9e-03 |
| group 3 medulloblastoma | 1.400 | 4.4e-04 |
| intraductal papillary-mucinous neoplasm ... | -1.100 | 6.5e-03 |
| lung cancer | 1.100 | 6.2e-04 |
| ovarian cancer | -1.500 | 1.3e-05 |
