Tbio SPOCD1 SPOC domain-containing protein 1

Protein Summary

Description

This gene encodes a protein that belongs to the TFIIS family of transcription factors. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Uniprot Accession IDs

• Q6ZMY3
• Q24JU3
• Q6PI90
• Q8N869
• Q8N8U0
• Q8NBC6
• Q96LN6

Gene Name

• SPOCD1

Ensembl ID

• ENST00000257100
• ENSP00000257100
• ENSG00000134668
• ENST00000360482
• ENSP00000353670
• ENST00000533231
• ENSP00000435851

Symbol

• PPP1R146

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.56
transcription factor	0.56
cell type or tissue	0.55
cellular component	0.52
transcription factor binding site profile	0.46

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Spoc Domain-containing Protein 1

Protein / Nucleic Acid Binding / Spoc Domain-containing Protein 1

DTO Classes

Protein / Nucleic Acid Binding / Spoc Domain-containing Protein 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.3   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 25   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.3   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 25   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0