Tbio SPESP1 Sperm equatorial segment protein 1

Protein Summary

Description

Involved in fertilization ability of sperm. The encoded protein is a human alloantigen involved in sperm-egg binding and fusion. [provided by RefSeq, Apr 2010]

Uniprot Accession IDs

• Q6UW49
• Q8NG22
• Q8WVH8
• SP-ESP

Gene Name

• SPESP1

Ensembl ID

• ENST00000310673
• ENSP00000312284
• ENSG00000258484

Symbol

• ESP
• SP-ESP

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.8
gene perturbation	0.56
cell type or tissue	0.54
PubMedID	0.54
cellular component	0.51

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1928.42   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 77   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1928.42   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 77   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0