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Tbio
SNX20
Sorting nexin-20

Protein Summary
Description
May play a role in cellular vesicle trafficking. Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, or on SELPLG-mediated cell-cell adhesion. SNX20 interacts with the cytoplasmic domain of PSGL1 (SELPLG; MIM 600738) and cycles PSGL1 into endosomes.[supplied by OMIM, Feb 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000300590
  • ENSP00000300590
  • ENSG00000167208
  • ENST00000330943
  • ENSP00000332062
  • ENST00000423026
  • ENSP00000388875
  • ENST00000568993
  • ENSP00000454863

Symbol
  • SLIC1
  • SLIC1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.76
tissue sample
0.71
microRNA
0.67
tissue
0.44
cell line
0.42


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.97   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 74   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.97   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 74   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0