| Tdark | U2 small nuclear ribonucleoprotein B'' |
Involved in pre-mRNA splicing. This protein is associated with snRNP U2. It binds stem loop IV of U2 snRNA only in presence of the U2A' protein.
The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| sonic hedgehog group medulloblastoma | 467 | 7.6e-07 |
| lung cancer | 4740 | 4.3e-03 |
| breast carcinoma | 1638 | 3.0e-02 |
| Disease | log2 FC | p |
|---|---|---|
| breast carcinoma | 1.100 | 3.0e-02 |
| lung cancer | 1.700 | 4.3e-03 |
| sonic hedgehog group medulloblastoma | 1.200 | 7.6e-07 |
| Accession | P08579 B2R7J3 D3DW21 Q9UJD4 U2 snRNP B'' |
| Symbols |
Msl1 U2B'' |
